Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | PDE4A | P27815 | 1/20 | 0.59 |
| ▸ | BLVRB | P30043 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.57 |
| ▸ | THRB | P10828 | 3/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | APP | P05067 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | CD69 | Q07108 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10334179 | 1.00 | KMT2A (0.59) | KMT2AMEN1PDE4ABLVRBKDR | |
| SCHEMBL3385330 | 0.91 | MEN1 (0.70) | KMT2AMEN1PDE4ABLVRBKDR | |
| SCHEMBL26730466 | 0.91 | MEN1 (0.70) | KMT2AMEN1PDE4ABLVRBKDR | |
| SCHEMBL1624756 | 0.91 | MEN1 (0.70) | KMT2AMEN1PDE4ABLVRBKDR | |
| SCHEMBL10930328 | 0.89 | MEN1 (0.68) | KMT2AMEN1PDE4ABLVRBKDR | |
| SCHEMBL16899826 | 0.86 | MEN1 (0.82) | KMT2AMEN1PDE4ABLVRBKDR | |
| SCHEMBL16899827 | 0.86 | MEN1 (0.82) | KMT2AMEN1PDE4ABLVRBKDR | |
| SCHEMBL6934004 | 0.85 | TRPA1 (0.62) | KMT2AMEN1PDE4ABLVRBKDR | |
| SCHEMBL1624852 | 0.84 | MEN1 (0.85) | KMT2AMEN1PDE4ABLVRBKDR | |
| SCHEMBL3386039 | 0.84 | MEN1 (0.85) | KMT2AMEN1PDE4ABLVRBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933330-A | PSORIASIS | DAK-LABORATORIET (DK) | 1990-06-12 | — | — | US | disclosed |
| EP-0291159-A2 | Aminosalicylic-acid derivatives for the treatment of psoriasis | DAK-LABORATORIET A/S (DK) | 1988-11-17 | — | — | EP | disclosed |