Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 6/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 6/20 | 1.00 |
| ▸ | XDH | P47989 | 6/20 | 1.00 |
| ▸ | FTO | Q9C0B1 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 6/20 | 1.00 |
| ▸ | GAA | P10253 | 6/20 | 1.00 |
| ▸ | APP | P05067 | 5/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 5/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 1.00 |
| ▸ | BACE1 | P56817 | 5/20 | 1.00 |
| ▸ | POLB | P06746 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | HPGD | P15428 | 4/20 | 1.00 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 1.00 |
| ▸ | DAPK1 | P53355 | 4/20 | 1.00 |
| ▸ | CSNK2B | P67870 | 4/20 | 1.00 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morin SCHEMBL29435805 | 1.00 | MEN1 (1.00) | MEN1KMT2ACYP3A4CYP2C9XDH | |
| Morin SCHEMBL19984 | 1.00 | MEN1 (1.00) | MEN1KMT2ACYP3A4CYP2C9XDH | |
| Morin SCHEMBL29929115 | 1.00 | MEN1 (1.00) | MEN1KMT2ACYP3A4CYP2C9XDH | |
| Morin SCHEMBL294933 | 0.98 | MPG (1.00) | MEN1KMT2ACYP3A4CYP2C9XDH | |
| Morin SCHEMBL29400568 | 0.98 | MPG (1.00) | MEN1KMT2ACYP3A4CYP2C9XDH | |
| Morin SCHEMBL7116848 | 0.98 | MPG (1.00) | MEN1KMT2ACYP3A4CYP2C9XDH | |
| Morin SCHEMBL21874430 | 0.98 | MEN1 (0.97) | MEN1KMT2ACYP3A4CYP2C9XDH | |
| Morin SCHEMBL15106661 | 0.98 | MPG (1.00) | MEN1KMT2ACYP3A4CYP2C9XDH | |
| Morin SCHEMBL8165525 | 0.94 | MEN1 (0.89) | MEN1KMT2ACYP3A4CYP2C9XDH | |
| Morin SCHEMBL5248628 | 0.93 | MEN1 (0.89) | MEN1KMT2ACYP3A4CYP2C9XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290442-A4 | PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS. | CHEMEX PHARMACEUTICALS INC (US) | 1990-07-03 | — | — | EP | claimed |
| EP-0290442-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS | CHEMEX PHARMACEUTICALS, INC. (US) | 1988-11-17 | — | — | EP | claimed |
| WO-1988003805-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS | CHEMEX PHARMACEUTICALS, INC. (US) | 1988-06-02 | — | — | WO | claimed |
| US-11744820-B2 | Inhibitors of microbially induced amyloid | AXIAL THERAPEUTICS, INC. (US) | 2023-09-05 | — | — | US | disclosed |
| US-11147792-B2 | Inhibitors of microbially induced amyloid | AXIAL THERAPEUTICS, INC. (US) | 2021-10-19 | — | — | US | disclosed |
| US-20200163933-A1 | INHIBITORS OF MICROBIALLY INDUCED AMYLOID | AXIAL BIOTHERAPEUTICS, INC. | 2020-05-28 | — | — | US | disclosed |
| EP-3624782-A1 | INHIBITORS OF MICROBIALLY INDUCED AMYLOID | Axial Biotherapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |
| WO-2018213204-A1 | INHIBITORS OF MICROBIALLY INDUCED AMYLOID | AXIAL BIOTHERAPEUTICS, INC. (US) | 2018-11-22 | — | — | WO | disclosed |
| US-20140018552-A1 | USE OF COMPOUNDS ISOLATED FROM MORUS BARK | DONG WHA PHARM. CO., LTD. (KR) | 2014-01-16 | — | — | US | disclosed |
| EP-0290442-A4 | PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS. | CHEMEX PHARMACEUTICALS INC (US) | 1990-07-03 | — | — | EP | disclosed |
| EP-0290442-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS | CHEMEX PHARMACEUTICALS, INC. (US) | 1988-11-17 | — | — | EP | disclosed |
| WO-1988003805-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS | CHEMEX PHARMACEUTICALS, INC. (US) | 1988-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018552-A1 | USE OF COMPOUNDS ISOLATED FROM MORUS BARK | AGER, MORF4L1, HNRNPF | MEN1 3938/4885KMT2A 2385/4885CYP3A4 3690/4885 |
| US-11744820-B2 | Inhibitors of microbially induced amyloid | APP, PSEN1, BACE1 | MEN1 3857/4885KMT2A 4653/4885CYP3A4 3546/4885 |
| US-20200163933-A1 | INHIBITORS OF MICROBIALLY INDUCED AMYLOID | APP, PSEN1, BACE1 | MEN1 3857/4885KMT2A 4653/4885CYP3A4 3546/4885 |
| US-11147792-B2 | Inhibitors of microbially induced amyloid | APP, PSEN1, BACE1 | MEN1 3857/4885KMT2A 4653/4885CYP3A4 3546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.