Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | CYP1A1 | P04798 | 7/20 | 0.62 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.62 |
| ▸ | XDH | P47989 | 5/20 | 0.62 |
| ▸ | APP | P05067 | 5/20 | 0.62 |
| ▸ | IPMK | Q8NFU5 | 5/20 | 0.62 |
| ▸ | IP6K2 | Q9UHH9 | 5/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.62 |
| ▸ | RECQL | P46063 | 4/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isorhamnetin SCHEMBL28113738 | 0.90 | CYP1A1 (0.66) | MEN1KMT2ACYP3A4CYP1A2HSD17B10 | |
| Fisetin SCHEMBL23282487 | 0.87 | CYP3A4 (0.62) | MEN1KMT2ACYP3A4CYP1A2HSD17B10 | |
| Quercetin SCHEMBL220351 | 0.84 | CYP3A4 (0.63) | MEN1KMT2ACYP3A4CYP1A2HSD17B10 | |
| Quercetin SCHEMBL4436805 | 0.84 | CYP3A4 (0.62) | MEN1KMT2ACYP3A4CYP1A2HSD17B10 | |
| Quercetin SCHEMBL28118226 | 0.83 | MEN1 (0.61) | MEN1KMT2ACYP3A4CYP1A2HSD17B10 | |
| Quercetin SCHEMBL4173190 | 0.80 | MEN1 (0.87) | MEN1KMT2ACYP3A4CYP1A2HSD17B10 | |
| Quercetin SCHEMBL3958393 | 0.80 | MEN1 (0.87) | MEN1KMT2ACYP3A4CYP1A2HSD17B10 | |
| Quercetin SCHEMBL31507620 | 0.79 | MEN1 (1.00) | MEN1KMT2ACYP3A4CYP1A2HSD17B10 | |
| Quercetin SCHEMBL118425 | 0.79 | MEN1 (1.00) | MEN1KMT2ACYP3A4CYP1A2HSD17B10 | |
| Quercetin SCHEMBL29723041 | 0.79 | MEN1 (1.00) | MEN1KMT2ACYP3A4CYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290442-A4 | PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS. | CHEMEX PHARMACEUTICALS INC (US) | 1990-07-03 | — | — | EP | disclosed |
| EP-0290442-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS | CHEMEX PHARMACEUTICALS, INC. (US) | 1988-11-17 | — | — | EP | disclosed |
| WO-1988003805-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS | CHEMEX PHARMACEUTICALS, INC. (US) | 1988-06-02 | — | — | WO | disclosed |