Isorhamnetin

Isorhamnetin

SCHEMBL28113738

COc1cc(-c2oc3cc(O)cc(O)c3c(=O)c2O)ccc1O.O=C1CC(c2ccccc2)Oc2ccccc21

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 6/20 0.66
CYP1A2 P05177 6/20 0.66
CYP1B1 Q16678 6/20 0.66
MEN1 O00255 4/20 0.66
KMT2A Q03164 4/20 0.66
CA12 O43570 3/20 0.66
CA4 P22748 3/20 0.66
PPARG P37231 3/20 0.66
CA7 P43166 3/20 0.66
XDH P47989 3/20 0.66
CA2 P00918 2/20 0.66
IPMK Q8NFU5 2/20 0.66
IP6K2 Q9UHH9 2/20 0.66
ABCC1 P33527 2/20 0.57
ABCB1 P08183 4/20 0.52
MMP9 P14780 2/20 0.51
NOX4 Q9NPH5 2/20 0.51
MAOA P21397 3/20 0.50
FTO Q9C0B1 3/20 0.50
POLB P06746 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quercetin SCHEMBL10335403 0.90 MEN1 (0.62) CYP1A1CYP1A2CYP1B1MEN1KMT2A
Isorhamnetin SCHEMBL29377152 0.81 MEN1 (1.00) CYP1A1CYP1A2CYP1B1MEN1KMT2A
Isorhamnetin SCHEMBL30385934 0.81 MEN1 (1.00) CYP1A1CYP1A2CYP1B1MEN1KMT2A
Isorhamnetin SCHEMBL19235 0.81 MEN1 (1.00) CYP1A1CYP1A2CYP1B1MEN1KMT2A
Isorhamnetin SCHEMBL29390102 0.81 MEN1 (1.00) CYP1A1CYP1A2CYP1B1MEN1KMT2A
Homoeriodictyol SCHEMBL19127668 0.78 CYP1A1 (0.81) CYP1A1CYP1A2CYP1B1MEN1KMT2A
Isorhamnetin SCHEMBL28182051 0.78 MEN1 (0.93) CYP1A1CYP1A2CYP1B1MEN1KMT2A
Isorhamnetin SCHEMBL3715283 0.78 MEN1 (0.93) CYP1A1CYP1A2CYP1B1MEN1KMT2A
Fisetin SCHEMBL23282487 0.78 CYP3A4 (0.62) CYP1A1CYP1A2CYP1B1MEN1KMT2A
Isorhamnetin SCHEMBL20400224 0.77 MEN1 (0.78) CYP1A1CYP1A2CYP1B1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107074900-A Saccharide and saccharide compositions and mixtures 希乐克公司 2017-08-18 CN disclosed
CN-107074898-A Saccharide and saccharide compositions and mixtures 希乐克公司 2017-08-18 CN disclosed
CN-106232110-A Ion channel activation agent and using method 弗莱克斯制药股份有限公司 2016-12-14 CN disclosed