Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | TTR | P02766 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.43 |
| ▸ | CBR1 | P16152 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1368781 | 0.96 | TDP1 (0.47) | TDP1TTRMAPTHPGDSLC6A2 | |
| SCHEMBL4372626 | 0.90 | TDP1 (0.51) | TDP1TTRMAPTHPGDSLC6A2 | |
| SCHEMBL29892533 | 0.90 | TDP1 (0.51) | TDP1TTRMAPTHPGDSLC6A2 | |
| SCHEMBL9494486 | 0.86 | TDP1 (0.49) | TDP1TTRMAPTHPGDSLC6A2 | |
| SCHEMBL10791289 | 0.85 | TDP1 (0.40) | TDP1TTRMAPTHPGDSLC6A2 | |
| SCHEMBL6330127 | 0.81 | TDP1 (0.45) | TDP1TTRMAPTHPGDSLC6A2 | |
| SCHEMBL11330494 | 0.80 | TDP1 (0.44) | TDP1TTRMAPTHPGDSLC6A2 | |
| SCHEMBL1368776 | 0.80 | TDP1 (0.50) | TDP1TTRMAPTHPGDSLC6A2 | |
| SCHEMBL9493767 | 0.80 | TDP1 (0.50) | TDP1TTRMAPTHPGDSLC6A2 | |
| SCHEMBL28995 | 0.79 | TDP1 (0.67) | TDP1HPGDNR1I2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0357639-A4 | PROCESS FOR THE PREPARATION OF ALKYL DIARYL PHOSPHITES AND DIARYL HALOPHOSPHATES. | AKZO NV (NL) | 1990-04-17 | — | — | EP | disclosed |
| EP-0357639-A1 | PROCESS FOR THE PREPARATION OF ALKYL DIARYL PHOSPHITES AND DIARYL HALOPHOSPHATES | AKZO N.V. (NL) | 1990-03-14 | — | — | EP | disclosed |
| US-4820853-A | Process for the preparation of alkyl diaryl phosphites and diaryl halophosphates | AKZO AMERICA INC. (US) | 1989-04-11 | — | — | US | disclosed |
| WO-1988007046-A1 | PROCESS FOR THE PREPARATION OF ALKYL DIARYL PHOSPHITES AND DIARYL HALOPHOSPHATES | AKZO N.V. (NL) | 1988-09-22 | — | — | WO | disclosed |