SCHEMBL1368776

SCHEMBL1368776

O=P(Cl)(Oc1ccc(Cl)cc1Cl)Oc1ccc(Cl)cc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.50
TTR P02766 3/20 0.46
HPGD P15428 2/20 0.46
NR1I2 O75469 1/20 0.46
LMNA P02545 1/20 0.46
PGR P06401 1/20 0.46
HSP90AA1 P07900 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
MAPT P10636 1/20 0.46
HSPA5 P11021 1/20 0.46
CBR1 P16152 1/20 0.46
TBXA2R P21731 1/20 0.46
SLC6A2 P23975 1/20 0.46
AGTR1 P30556 1/20 0.46
SLC6A3 Q01959 1/20 0.46
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
GAA P10253 1/20 0.42
MAPK1 P28482 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9493767 0.88 TDP1 (0.50) TDP1TTRHPGDNR1I2LMNA
SCHEMBL4372626 0.85 TDP1 (0.51) TDP1TTRHPGDNR1I2LMNA
SCHEMBL29892533 0.85 TDP1 (0.51) TDP1TTRHPGDNR1I2LMNA
SCHEMBL10935492 0.84 TDP1 (0.65) TDP1HPGDNR1I2MAPTMEN1
SCHEMBL6330123 0.84 TDP1 (0.47) TDP1TTRHPGDNR1I2LMNA
SCHEMBL11441578 0.84 TDP1 (0.51) TDP1TTRHPGDNR1I2LMNA
SCHEMBL3235427 0.82 TDP1 (0.49) TDP1TTRHPGDNR1I2LMNA
SCHEMBL4372630 0.82 INPPL1 (0.52) TDP1TTRHPGDNR1I2LMNA
SCHEMBL11101053 0.82 TDP1 (0.49) TDP1TTRHPGDNR1I2LMNA
SCHEMBL9494486 0.82 TDP1 (0.49) TDP1TTRHPGDNR1I2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8729260-B2 Process for the preparation of carbapenem using cabapenem intermediates and recovery of cabapenem SAVIOR LIFETEC CORPORATION (TW) 2014-05-20 US claimed
US-20110288290-A1 PROCESS FOR THE PREPARATION OF CARBAPENEM USING CABAPENEM INTERMEDIATES AND RECOVERY OF CABAPENEM SAVIOR LIFETEC CORPORATION (TW) 2011-11-24 US claimed
US-20110288289-A1 Preparation of Carbapenem Intermediate and Their Use SAVIOR LIFETEC CORPORATION (TW) 2011-11-24 US claimed
EP-2388261-A2 Improved process for the preparation of carbapenem using carbapenem intermediates and recovery of carbapenem Savior Lifetec Corporation (TW) 2011-11-23 EP claimed
US-D647009-S1 Motor vehicle and/or toy replica thereof TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2011-10-18 US claimed
US-6863592-B2 Chemical/mechanical polishing slurry and chemical mechanical polishing method using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2005-03-08 US claimed
US-20040033764-A1 Chemical/mechanical polishing slurry and chemical mechanical polishing method using the same SAMSUNG ELECTRONICS CO., LTD. 2004-02-19 US claimed
US-20030148616-A1 Chemical/mechanical polishing slurry, and chemical mechanical polishing process and shallow trench isolation process employing the same LEE JONG-WON (KR) 2003-08-07 US claimed
US-6540935-B2 Chemical/mechanical polishing slurry, and chemical mechanical polishing process and shallow trench isolation process employing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2003-04-01 US claimed
US-20030022499-A1 Chemical/mechanical polishing slurry, and chemical mechanical polishing process and shallow trench isolation process employing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2003-01-30 US claimed
US-5245069-A Reacting a phosphoryl halide and a phenol in the presence of a dialkylaminopyridine and an arylphosphorodihalidate MERCK & CO., INC. (US) 1993-09-14 US claimed
EP-0429726-A1 Process for 2-(aminoalkylthio)carbapenems MERCK & CO. INC. (US) 1991-06-05 EP claimed
US-4894450-A FORMING AN ENOL PHOSPHATE INTERMEDIATE MERCK & CO., INC. (US) 1990-01-16 US claimed
US-4845261-A Process for bis(substituted phenyl) phosphorohalidates MERCK & CO., INC. (US) 1989-07-04 US claimed
US-20260015372-A1 Organophosphorous Compounds and Uses Thereof JAL THERAPEUTICS LLC (US) 2026-01-15 US disclosed
US-20250215264-A1 SLURRY COMPOSITION FOR CHEMICAL MECHANICAL POLISHING, METHOD OF PREPARING SAME, AND CHEMICAL MECHANICAL POLISHING METHOD OF WAFER SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-07-03 US disclosed
US-20250043149-A1 SLURRY COMPOSITION FOR CHEMICAL MECHANICAL POLISHING AND CHEMICAL MECHANICAL POLISHING APPARATUS SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-02-06 US disclosed
US-4845261-A Process for bis(substituted phenyl) phosphorohalidates MERCK & CO., INC. (US) 1989-07-04 US disclosed
US-4820853-A Process for the preparation of alkyl diaryl phosphites and diaryl halophosphates AKZO AMERICA INC. (US) 1989-04-11 US disclosed
WO-1988007046-A1 PROCESS FOR THE PREPARATION OF ALKYL DIARYL PHOSPHITES AND DIARYL HALOPHOSPHATES AKZO N.V. (NL) 1988-09-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110288289-A1 Preparation of Carbapenem Intermediate and Their Use SI, MGAM, IDE TDP1 4686/4885TTR 3333/4885HPGD 217/4885
US-20110288290-A1 PROCESS FOR THE PREPARATION OF CARBAPENEM USING CABAPENEM INTERMEDIATES AND RECOVERY OF CABAPENEM MGAM, PMM2, PYGM TDP1 4695/4885TTR 3834/4885HPGD 1435/4885
US-20260015372-A1 Organophosphorous Compounds and Uses Thereof ACHE, BCHE, MUSK TDP1 296/4885TTR 1236/4885HPGD 3786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.