SCHEMBL10336366

SCHEMBL10336366

CC(=O)c1ccc(N(C)C)cc1.CN(C)c1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.85
HPGD P15428 3/20 0.85
NPC1 O15118 3/20 0.85
MAPT P10636 6/20 0.70
ALDH1A1 P00352 6/20 0.70
KDM4E B2RXH2 2/20 0.61
MAPK1 P28482 1/20 0.61
KMT2A Q03164 4/20 0.56
MEN1 O00255 2/20 0.56
GFER P55789 1/20 0.53
SMN1; SMN2 Q16637 4/20 0.52
HTT P42858 2/20 0.51
LMNA P02545 2/20 0.51
KCNK3 O14649 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
POLB P06746 1/20 0.51
NFKB1 P19838 1/20 0.51
NFKB2 Q00653 1/20 0.51
RELA Q04206 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43585 0.92 HPGD (1.00) RAB9AHPGDNPC1MAPTALDH1A1
SCHEMBL28230346 0.92 HPGD (1.00) RAB9AHPGDNPC1MAPTALDH1A1
Michler'S Ketone SCHEMBL3324670 0.92 HPGD (1.00) RAB9AHPGDNPC1MAPTALDH1A1
Hydrochloric Acid SCHEMBL10950983 0.90 HPGD (0.96) RAB9AHPGDNPC1MAPTALDH1A1
Acetophenone SCHEMBL27096615 0.89 RAB9A (0.67) RAB9AHPGDNPC1MAPTALDH1A1
Acetophenone SCHEMBL27863499 0.88 RAB9A (0.64) RAB9AHPGDNPC1MAPTALDH1A1
Benzophenone SCHEMBL28424466 0.87 HPGD (0.89) RAB9AHPGDNPC1MAPTALDH1A1
SCHEMBL12757170 0.87 HPGD (0.89) RAB9AHPGDNPC1MAPTALDH1A1
Michler'S Ketone SCHEMBL10883748 0.87 RAB9A (0.89) RAB9AHPGDNPC1MAPTALDH1A1
Benzophenone SCHEMBL27838742 0.86 HPGD (0.88) RAB9AHPGDNPC1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4923781-A STORAGE STABILITY, CONTRAST, HIGH DENSITY, PHOTOSENSITIVITY FUJI PHOTO FILM CO., LTD. (JP) 1990-05-08 US disclosed