Michler'S Ketone

Michler'S Ketone

SCHEMBL3324670

CN(C)c1ccc(C(=O)c2ccc(N(C)C)cc2)cc1.O=C(c1ccccc1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 1.00
RAB9A P51151 3/20 1.00
NPC1 O15118 3/20 1.00
ALDH1A1 P00352 6/20 0.83
MAPT P10636 4/20 0.83
KMT2A Q03164 4/20 0.64
MEN1 O00255 3/20 0.64
GFER P55789 1/20 0.60
SRD5A2 P31213 1/20 0.58
KDM4E B2RXH2 1/20 0.58
SMN1; SMN2 Q16637 2/20 0.57
POLB P06746 2/20 0.57
KCNK3 O14649 1/20 0.57
LMNA P02545 1/20 0.57
NFKB1 P19838 1/20 0.57
HTT P42858 1/20 0.57
NFKB2 Q00653 1/20 0.57
RELA Q04206 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
CASP3 P42574 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28230346 1.00 HPGD (1.00) HPGDRAB9ANPC1ALDH1A1MAPT
SCHEMBL43585 1.00 HPGD (1.00) HPGDRAB9ANPC1ALDH1A1MAPT
Hydrochloric Acid SCHEMBL10950983 0.98 HPGD (0.96) HPGDRAB9ANPC1ALDH1A1MAPT
SCHEMBL12757170 0.94 HPGD (0.89) HPGDRAB9ANPC1ALDH1A1MAPT
Michler'S Ketone SCHEMBL10883748 0.94 RAB9A (0.89) HPGDRAB9ANPC1ALDH1A1MAPT
Benzophenone SCHEMBL28424466 0.94 HPGD (0.89) HPGDRAB9ANPC1ALDH1A1MAPT
Benzophenone SCHEMBL27838742 0.93 HPGD (0.88) HPGDRAB9ANPC1ALDH1A1MAPT
SCHEMBL10336366 0.92 RAB9A (0.85) HPGDRAB9ANPC1ALDH1A1MAPT
Michler'S Ketone SCHEMBL36517 0.91 ALDH1A1 (1.00) HPGDRAB9ANPC1ALDH1A1MAPT
SCHEMBL274966 0.91 ALDH1A1 (1.00) HPGDRAB9ANPC1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3445826-B1 RADIATION CURABLE INK FORMULATION FLINT GROUP GERMANY GMBH (DE) 2021-07-14 EP disclosed
US-20190106583-A1 RADIATION CURABLE INK FORMULATION FLINT GROUP SWEDEN AB (SE) 2019-04-11 US disclosed
US-10252291-B2 Photo-curing of thermoplastic coatings COLOPLAST A/S (DK) 2019-04-09 US disclosed
US-10040893-B2 Polymeric photoinitiators and photoinitiator monomers COLOPLAST A/S (DK) 2018-08-07 US disclosed
US-10040902-B2 Polymeric photoinitiators COLOPLAST A/S (DK) 2018-08-07 US disclosed
US-10011688-B2 Hydrophilic gels derived from grafted photoinitiators COLOPLAST A/S (DK) 2018-07-03 US disclosed
WO-2017182638-A1 RADIATION CURABLE INK FORMULATION FLINT GROUP GERMANY GMBH (DE) 2017-10-26 WO disclosed
US-9708425-B2 Routes to polyacrylates COLOPLAST A/S (DK) 2017-07-18 US disclosed
US-9670373-B2 Polymers comprising photoinitiator moieties and dye moieties LAMBSON LIMITED (GB) 2017-06-06 US disclosed
US-9464143-B2 Grafted photoinitiators COLOPLAST A/S (DK) 2016-10-11 US disclosed
US-20130096220-A1 GRAFTED PHOTOINITIATORS COLOPLAST A/S (DK) 2013-04-18 US disclosed
US-20130090406-A1 HYDROPHILIC GELS FROM POLYALKYLETHER-BASED PHOTOINITIATORS COLOPLAST A/S (DK) 2013-04-11 US disclosed
US-20130089582-A1 HYDROPHILIC GELS FROM POLYURETHANE-BASED PHOTOINITIATORS COLOPLAST A/S (DK) 2013-04-11 US disclosed
US-20130089581-A1 SKIN-FRIENDLY ADHESIVES FROM POLYALKLETHER-BASED PHOTOINITIATORS COLOPLAST A/S (DK) 2013-04-11 US disclosed
US-20130059940-A1 POLYMERIC PHOTOINITIATORS COLOPLAST A/S (DK) 2013-03-07 US disclosed
US-20120121919-A1 MEDICAL DEVICE OF POLYOLEFIN COLOPLAST A/S (DK) 2012-05-17 US disclosed
US-20100119833-A1 PHOTO-CURING OF THERMOPLASTIC COATINGS MADSEN NIELS JORGEN 2010-05-13 US disclosed
US-20100049146-A1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS COLOPLAST A/S (DK) 2010-02-25 US disclosed
US-4137084-A Process for producing pressure-sensitive copy sheets using novel radiation curable coatings THE MEAD CORPORATION (US) 1979-01-30 US disclosed
US-4097619-A Manifold carbonless form and process for the continuous production thereof THE MEAD CORPORATION (US) 1978-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10040893-B2 Polymeric photoinitiators and photoinitiator monomers ACMSD, AAAS, PPOX HPGD 2444/4885RAB9A 3260/4885NPC1 4505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.