Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.38 |
| ▸ | THRA | P10827 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PCNA | P12004 | 1/20 | 0.34 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.34 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.34 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.34 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.34 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1033757 | 0.96 | SCN9A (0.35) | EGLN1THRATHRBSCN9AEGLN2 | |
| SCHEMBL1030683 | 0.85 | SMN1; SMN2 (0.47) | EGLN1THRATHRBNPC1RAB9A | |
| SCHEMBL523022 | 0.83 | EGLN1 (0.51) | EGLN1THRATHRBEGLN2BBOX1 | |
| SCHEMBL1032619 | 0.82 | THRA (0.39) | EGLN1THRATHRBEGLN2NPC1 | |
| SCHEMBL1033387 | 0.82 | FTO (0.46) | EGLN1THRATHRBEGLN2BBOX1 | |
| SCHEMBL4078616 | 0.82 | EGLN1 (0.41) | EGLN1THRATHRBNPC1RAB9A | |
| SCHEMBL1033585 | 0.81 | THRA (0.41) | EGLN1THRATHRBNPC1RAB9A | |
| SCHEMBL1033120 | 0.81 | SMN1; SMN2 (0.47) | EGLN1THRATHRBNPC1RAB9A | |
| SCHEMBL1032319 | 0.81 | THRA (0.38) | EGLN1THRATHRBNPC1RAB9A | |
| SCHEMBL523248 | 0.78 | EGLN1 (0.49) | EGLN1THRATHRBEGLN2BBOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644336-B1 | NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND THEIR USE IN INCREASING ENDOGENEOUS ERYTHROPOIETIN | FIBROGEN INC (US) | 2011-01-19 | — | — | EP | claimed |