Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9643015 | 0.88 | ABCB11 (0.63) | ABCB11MAPTDHODH | |
| SCHEMBL9642245 | 0.85 | ABCB11 (0.54) | ABCB11MAPTDHODH | |
| SCHEMBL10337090 | 0.85 | ABCB11 (0.54) | ABCB11MAPTDHODH | |
| SCHEMBL9642915 | 0.82 | ABCB11 (0.49) | ABCB11MAPTDHODH | |
| SCHEMBL9643064 | 0.81 | ABCB11 (0.54) | ABCB11MAPTDHODH | |
| SCHEMBL9642690 | 0.81 | ABCB11 (0.54) | ABCB11MAPTDHODH | |
| SCHEMBL9643105 | 0.81 | ABCB11 (0.54) | ABCB11DHODH | |
| SCHEMBL9641821 | 0.81 | ABCB11 (0.54) | ABCB11DHODH | |
| SCHEMBL9642402 | 0.77 | ABCB11 (0.55) | ABCB11DHODH | |
| SCHEMBL9643104 | 0.77 | ABCB11 (0.55) | ABCB11DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4946845-A | STABLE ANTIINFLAMMATORY AGENTS, LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1990-08-07 | — | — | US | disclosed |
| US-4792556-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0215622-A2 | Naphthalene anti-psoriatic agents and process for making them | SYNTEX (U.S.A.) INC. (US) | 1987-03-25 | — | — | EP | disclosed |