Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 8/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9641821 | 1.00 | ABCB11 (0.54) | ABCB11PTGER1PTGS2DHODHADORA3 | |
| SCHEMBL9643015 | 0.92 | ABCB11 (0.63) | ABCB11DHODHSMN1; SMN2KDM5AKDM4C | |
| SCHEMBL10337090 | 0.86 | ABCB11 (0.54) | ABCB11DHODHSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9642245 | 0.86 | ABCB11 (0.54) | ABCB11DHODHSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9642690 | 0.85 | ABCB11 (0.54) | ABCB11DHODHSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9643064 | 0.85 | ABCB11 (0.54) | ABCB11DHODHSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9643097 | 0.84 | ABCB11 (0.54) | ABCB11PTGER1DHODHALDH1A1 | |
| SCHEMBL9641815 | 0.84 | ABCB11 (0.54) | ABCB11PTGER1DHODHALDH1A1 | |
| SCHEMBL9643533 | 0.83 | ABCB11 (0.70) | ABCB11PTGER1DHODHADORA3 | |
| SCHEMBL9642402 | 0.82 | ABCB11 (0.55) | ABCB11DHODHSMN1; SMN2KDM5AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215622-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS AND PROCESS FOR MAKING THEM | SYNTEX (U.S.A.) INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4946845-A | STABLE ANTIINFLAMMATORY AGENTS, LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1990-08-07 | — | — | US | disclosed |
| US-4792556-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0215622-A2 | Naphthalene anti-psoriatic agents and process for making them | SYNTEX (U.S.A.) INC. (US) | 1987-03-25 | — | — | EP | disclosed |