Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 18/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30007774 | 1.00 | BRD4 (0.50) | BRD4NPC1RAB9AALDH1A1HTT | |
| SCHEMBL4025539 | 0.75 | CA12 (0.55) | NPC1RAB9AALDH1A1 | |
| SCHEMBL17307543 | 0.75 | CA12 (0.48) | NPC1RAB9AALDH1A1 | |
| SCHEMBL6988890 | 0.73 | BRD4 (0.53) | BRD4 | |
| SCHEMBL29819513 | 0.73 | ALDH1A1 (0.58) | NPC1RAB9AALDH1A1HTT | |
| SCHEMBL4789839 | 0.72 | NPC1 (0.40) | NPC1RAB9AALDH1A1HTT | |
| SCHEMBL10306224 | 0.69 | ALDH1A1 (0.54) | NPC1RAB9AALDH1A1HTT | |
| SCHEMBL1027255 | 0.69 | BRD4 (0.41) | BRD4 | |
| SCHEMBL11204858 | 0.68 | NPC1 (0.55) | NPC1RAB9AALDH1A1HTT | |
| SCHEMBL30007699 | 0.68 | BRD4 (0.43) | BRD4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215856-A | Preparation method of PPAR delta agonist finadepa and intermediate thereof | 沈阳药科大学 | 2022-10-21 | — | — | CN | disclosed |
| EP-3424917-A1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR | Nippon Chemiphar Co., Ltd. (JP) | 2019-01-09 | — | — | EP | disclosed |
| EP-2277874-B1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR | NIPPON CHEMIPHAR CO (JP) | 2018-06-27 | — | — | EP | disclosed |
| US-8648208-B2 | Activating agent for peroxisome proliferator activated receptor | NIPPON CHEMIPHAR CO. LTD. (JP) | 2014-02-11 | — | — | US | disclosed |
| EP-2464349-A2 | USE OF PPAR DELTA LIGANDS FOR THE TREATMENT OR PREVENTION OF INFLAMMATION OR ENERGY METABOLISM/PRODUCTION RELATED DISEASES | Cerenis Therapeutics S.A. (FR) | 2012-06-20 | — | — | EP | disclosed |
| WO-2011020001-A9 | USE OF PPAR DELTA LIGANDS FOR THE TREATMENT OR PREVENTION OF INFLAMMATION OR ENERGY METABOLISM/PRODUCTION RELATED DISEASES | CERENIS THERAPEUTICS S.A. (FR) | 2011-05-26 | — | — | WO | disclosed |
| US-20110098480-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR | NIPPON CHEMIPHAR CO. LTD. (JP) | 2011-04-28 | — | — | US | disclosed |
| US-20110092517-A1 | Use of PPAR Delta Ligands for the Treatment or Prevention of Inflammation or Energy Metabolism/Production Related Diseases | Cerenis Therapeutics S.A. & Nippon Chemiphar Co., Ltd. | 2011-04-21 | — | — | US | disclosed |
| US-20110092517-A1 | Use of PPAR Delta Ligands for the Treatment or Prevention of Inflammation or Energy Metabolism/Production Related Diseases | Cerenis Therapeutics S.A. & Nippon Chemiphar Co., Ltd. | 2011-04-21 | — | — | US | disclosed |
| WO-2011020001-A2 | USE OF PPAR DELTA LIGANDS FOR THE TREATMENT OR PREVENTION OF INFLAMMATION OR ENERGY METABOLISM/PRODUCTION RELATED DISEASES | CERENIS THERAPEUTICS S.A. (FR) | 2011-02-17 | — | — | WO | disclosed |
| EP-2277874-A1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR | Nippon Chemiphar Co., Ltd. (JP) | 2011-01-26 | — | — | EP | disclosed |
| US-20100029949-A1 | Activator for Peroxisome Proliferator Activated Receptor | NIPPON CHEMIPHAR CO., LTD. (JP) | 2010-02-04 | — | — | US | disclosed |
| EP-1445258-B1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA | NIPPON CHEMIPHAR CO (JP) | 2009-06-24 | — | — | EP | disclosed |
| US-7402597-B2 | Activator of peroxisome proliferator-activated receptor δ | NIPPON CHEMIPHAR CO., LTD (JP) | 2008-07-22 | — | — | US | disclosed |
| EP-1916247-A1 | ACTIVATOR OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR | Nippon Chemiphar Co., Ltd. (JP) | 2008-04-30 | — | — | EP | disclosed |
| US-20070027196-A1 | Activator of peroxisome proliferator-activated receptor delta | SAKUMA SHOGO | 2007-02-01 | — | — | US | disclosed |
| US-7119104-B2 | Activator of peroxisome proliferator-activated receptor delta | NIPPON CHEMIPHAR, CO., LTD. (JP) | 2006-10-10 | — | — | US | disclosed |
| US-20050096363-A1 | Activator of peroxisome proliferator-activated receptor delta | NIPPON CHEMIPHAR CO., LTD. (JP) | 2005-05-05 | — | — | US | disclosed |
| EP-1445258-A1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA | NIPPON CHEMIPHAR CO., LTD. (JP) | 2004-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092517-A1 | Use of PPAR Delta Ligands for the Treatment or Prevention of Inflammation or Energy Metabolism/Production Related Diseases | PPARD, PPARG, PPARA | BRD4 2798/4885NPC1 4083/4885RAB9A 3292/4885 |
| US-20110098480-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR | PPARA, PPARG, PPARD | BRD4 59/4885NPC1 2187/4885RAB9A 3261/4885 |
| US-20100029949-A1 | Activator for Peroxisome Proliferator Activated Receptor | PPARA, PPARG, PPARD | BRD4 159/4885NPC1 1183/4885RAB9A 3200/4885 |
| US-20070027196-A1 | Activator of peroxisome proliferator-activated receptor delta | PPARA, PPARG, PPARD | BRD4 85/4885NPC1 2188/4885RAB9A 2515/4885 |
| US-20050096363-A1 | Activator of peroxisome proliferator-activated receptor delta | PPARA, PPARG, PPARD | BRD4 85/4885NPC1 2188/4885RAB9A 2515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.