Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.45 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.45 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.45 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.45 |
| ▸ | CBFB | Q13951 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17307543 | 0.88 | CA12 (0.48) | CA12CA1CA9MAP2K1ALDH1A1 | |
| SCHEMBL7902665 | 0.83 | CA12 (0.50) | CA12CA1CA9MAP2K1ALDH1A1 | |
| SCHEMBL17454400 | 0.83 | HIF1A (0.50) | CA12CA1CA9MAP2K1ALDH1A1 | |
| SCHEMBL6554510 | 0.82 | NR3C1 (0.52) | CA12CA1CA9MAP2K1ALDH1A1 | |
| SCHEMBL16571762 | 0.81 | CA12 (0.48) | CA12CA1CA9MAP2K1ALDH1A1 | |
| SCHEMBL17307563 | 0.80 | CA12 (0.60) | CA12CA1CA9ALDH1A1SMN1; SMN2 | |
| SCHEMBL16571545 | 0.80 | HIF1A (0.50) | CA12CA1CA9MAP2K1LMNA | |
| SCHEMBL17984615 | 0.80 | CA12 (0.47) | CA12CA1CA9MAP2K1ALDH1A1 | |
| SCHEMBL20229888 | 0.79 | POLB (0.49) | CA12CA1CA9MAP2K1ALDH1A1 | |
| SCHEMBL17984566 | 0.79 | CA12 (0.46) | CA12CA1CA9MAP2K1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221655-A1 | ANTIBACTERIAL AGENTS | PITZER, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| US-20090221655-A1 | ANTIBACTERIAL AGENTS | PITZER, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| US-20090221655-A1 | ANTIBACTERIAL AGENTS | PITZER, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| EP-1445258-B1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA | NIPPON CHEMIPHAR CO (JP) | 2009-06-24 | — | — | EP | disclosed |
| EP-2032565-A2 | BENZISOXAZOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | Pfizer Products Inc. (US) | 2009-03-11 | — | — | EP | disclosed |
| US-7402597-B2 | Activator of peroxisome proliferator-activated receptor δ | NIPPON CHEMIPHAR CO., LTD (JP) | 2008-07-22 | — | — | US | disclosed |
| WO-2007088438-A2 | BENZISOXAZOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PFIZER PRODUCTS INC. (US) | 2007-08-09 | — | — | WO | disclosed |
| US-20070027196-A1 | Activator of peroxisome proliferator-activated receptor delta | SAKUMA SHOGO | 2007-02-01 | — | — | US | disclosed |
| US-7119104-B2 | Activator of peroxisome proliferator-activated receptor delta | NIPPON CHEMIPHAR, CO., LTD. (JP) | 2006-10-10 | — | — | US | disclosed |
| US-20050096363-A1 | Activator of peroxisome proliferator-activated receptor delta | NIPPON CHEMIPHAR CO., LTD. (JP) | 2005-05-05 | — | — | US | disclosed |
| EP-1445258-A1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA | NIPPON CHEMIPHAR CO., LTD. (JP) | 2004-08-11 | — | — | EP | disclosed |
| US-20020032330-A1 | Propionic acid derivatives | NOMURA YUTAKA (JP) | 2002-03-14 | — | — | US | disclosed |
| EP-0994095-A1 | PROPIONIC ACID DERIVATIVES | NIPPON CHEMIPHAR CO., LTD. (JP) | 2000-04-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027196-A1 | Activator of peroxisome proliferator-activated receptor delta | PPARA, PPARG, PPARD | CA12 4494/4885CA1 4301/4885CA9 3965/4885 |
| US-20090221655-A1 | ANTIBACTERIAL AGENTS | OXSR1, CBR3, AOC3 | CA12 2635/4885CA1 3051/4885CA9 1048/4885 |
| US-20020032330-A1 | Propionic acid derivatives | ABAT, ACAT1, PDXK | CA12 3567/4885CA1 2869/4885CA9 2586/4885 |
| US-20050096363-A1 | Activator of peroxisome proliferator-activated receptor delta | PPARA, PPARG, PPARD | CA12 4494/4885CA1 4301/4885CA9 3965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.