Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9723797 | 0.81 | LPAR3 (0.37) | LPAR3LPAR2TSHRALDH1A1LMNA | |
| SCHEMBL528149 | 0.71 | LTA4H (0.41) | TSHRALDH1A1MAPT | |
| SCHEMBL14759523 | 0.71 | LTA4H (0.44) | LPAR3LPAR2TSHRALDH1A1MAPT | |
| SCHEMBL9275922 | 0.71 | LTA4H (0.44) | LPAR3LPAR2TSHRALDH1A1MAPT | |
| SCHEMBL464983 | 0.70 | MAPT (0.37) | ALDH1A1MAPT | |
| SCHEMBL8072122 | 0.69 | HRH3 (0.65) | TSHRALDH1A1MAPT | |
| SCHEMBL1021527 | 0.69 | HRH3 (0.65) | TSHRALDH1A1MAPT | |
| SCHEMBL9225059 | 0.69 | HRH3 (0.65) | TSHRALDH1A1MAPT | |
| SCHEMBL8432395 | 0.69 | LTA4H (0.42) | TSHRCHRNB2CHRNA7CHRNA4ALDH1A1 | |
| SCHEMBL5222819 | 0.69 | HRH3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920101-A | FOR ENHANCING PENETRATION OF PHYSIOLOGICALLY ACTIVE AGENTS THROUGH SKIN OR OTHER MEMBRANES | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1990-04-24 | — | — | US | disclosed |