Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10337202 | 0.81 | LPAR3 (0.39) | LPAR3LPAR2TSHRSLC2A1MAPT | |
| SCHEMBL8972595 | 0.76 | LMNA (0.42) | TSHRALDH1A1LMNA | |
| SCHEMBL20975489 | 0.73 | ALDH1A1 (0.42) | MAPTALDH1A1LMNA | |
| SCHEMBL323843 | 0.72 | ALDH1A1 (0.50) | LPAR3LPAR2TSHRMAPTALDH1A1 | |
| SCHEMBL11782938 | 0.72 | SMN1; SMN2 (0.50) | TSHRALDH1A1LMNA | |
| SCHEMBL28720836 | 0.72 | SMN1; SMN2 (0.50) | TSHRALDH1A1LMNA | |
| SCHEMBL9433442 | 0.72 | SMN1; SMN2 (0.50) | TSHRALDH1A1LMNA | |
| SCHEMBL4911938 | 0.71 | LMNA (0.49) | TSHRMAPTALDH1A1LMNA | |
| SCHEMBL5254606 | 0.69 | KEAP1 (0.52) | ALDH1A1 | |
| SCHEMBL28436311 | 0.68 | SPHK1 (0.43) | LPAR3LPAR2TSHRSLC2A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368933-B1 | COMPOSITIONS COMPRISING 1-OXO- OR THIOHYDROCARBYL SUBSTITUTED AZACYCLOALKANES | Whitby Research Incorporated (US) | 1992-10-14 | — | — | EP | disclosed |
| EP-0368933-A1 | COMPOSITIONS COMPRISING 1-OXO- OR THIOHYDROCARBYL SUBSTITUTED AZACYCLOALKANES | Whitby Research Incorporated (US) | 1990-05-23 | — | — | EP | disclosed |