SCHEMBL10337232

SCHEMBL10337232

Nc1ccc(N)c(Oc2cccc(Oc3ccccc3)c2)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.63
ALDH1A1 P00352 5/20 0.60
GAA P10253 3/20 0.60
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
MITF O75030 1/20 0.60
MAPT P10636 1/20 0.60
GFER P55789 1/20 0.60
NLRP1 Q9C000 1/20 0.60
NOD2 Q9HC29 1/20 0.60
MAOA P21397 1/20 0.53
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
NLRP3 Q96P20 1/20 0.53
CYP3A4 P08684 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
F10 P00742 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10337161 0.98 MAOB (0.61) MAOBALDH1A1GAAMEN1KMT2A
SCHEMBL31613229 0.93 MAOA (0.56) MAOBALDH1A1GAAMEN1KMT2A
SCHEMBL7774904 0.93 MAOA (0.56) MAOBALDH1A1GAAMEN1KMT2A
Hydrochloric Acid SCHEMBL10337159 0.91 MAOA (0.54) MAOBALDH1A1GAAMEN1KMT2A
SCHEMBL17506807 0.87 MAOB (0.59) MAOBALDH1A1GAAMEN1KMT2A
SCHEMBL28301654 0.86 MAOB (0.63) MAOBALDH1A1GAAMEN1KMT2A
SCHEMBL5013387 0.85 MAOA (0.56) MAOBALDH1A1GAAMEN1KMT2A
SCHEMBL21612709 0.83 GAA (0.68) MAOBALDH1A1GAAMEN1KMT2A
SCHEMBL17506824 0.81 ALDH1A1 (0.48) MAOBALDH1A1GAAMEN1KMT2A
SCHEMBL3647191 0.81 MAOB (0.95) MAOBALDH1A1GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-H754-H ARLOXY P-PHENYLENE DIAMINES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1990-03-06 US claimed