SCHEMBL1033728

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1036726	0.89	DRD4 (0.59)	DRD4SIGMAR1LMNASMN1; SMN2CXCR4
	SCHEMBL1033229	0.84	DRD4 (0.64)	DRD4MCHR1SIGMAR1SLC6A12TMEM97
	SCHEMBL1037205	0.83	PRKAA2 (0.59)	MCHR1SIGMAR1SLC6A12TMEM97CCR3
	SCHEMBL60695	0.83	HDAC1 (0.58)	DRD4MCHR1SIGMAR1SLC6A12TMEM97
	SCHEMBL62237	0.80	DRD4 (0.76)	DRD4MCHR1SIGMAR1SLC6A12TMEM97
	SCHEMBL1037177	0.78	PRKAA2 (0.58)	DRD4SLC6A12PRKAA2DRD2SLC6A13
	SCHEMBL16938670	0.77	DRD4 (0.62)	DRD4MCHR1SIGMAR1SLC6A12TMEM97
	SCHEMBL12227417	0.77	PRKAA2 (0.54)	PRKAA2DRD2
	SCHEMBL60786	0.75	DRD4 (0.54)	DRD4MCHR1SIGMAR1SLC6A12TMEM97
	SCHEMBL2386411	0.75	DRD4 (0.66)	DRD4MCHR1SIGMAR1SLC6A12TMEM97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.