SCHEMBL10337353

SCHEMBL10337353

CCCCCCCCCCCCCCCC1CCOC(=O)N1

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.50
ALDH1A1 P00352 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
EPHX1 P07099 1/20 0.42
S1PR2 O95136 1/20 0.40
S1PR4 O95977 1/20 0.40
S1PR1 P21453 1/20 0.40
S1PR3 Q99500 1/20 0.40
S1PR5 Q9H228 1/20 0.40
HLCS P50747 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8392318 1.00 CYP1A2 (0.50) CYP1A2ALDH1A1L3MBTL1EPHX1S1PR2
SCHEMBL6036825 0.83 ALDH1A1 (0.47) CYP1A2ALDH1A1L3MBTL1EPHX1S1PR2
SCHEMBL474085 0.83 ALDH1A1 (0.47) CYP1A2ALDH1A1L3MBTL1EPHX1S1PR2
SCHEMBL2780724 0.83 ALDH1A1 (0.47) CYP1A2ALDH1A1L3MBTL1EPHX1S1PR2
SCHEMBL13082563 0.83 ALDH1A1 (0.47) CYP1A2ALDH1A1L3MBTL1EPHX1S1PR2
SCHEMBL10337476 0.83 ALDH1A1 (0.47) CYP1A2ALDH1A1L3MBTL1EPHX1S1PR2
SCHEMBL8443031 0.81 ALDH1A1 (0.45) CYP1A2ALDH1A1L3MBTL1S1PR2S1PR4
SCHEMBL5518415 0.81 ALDH1A1 (0.45) CYP1A2ALDH1A1L3MBTL1S1PR2S1PR4
SCHEMBL9052248 0.81 ALDH1A1 (0.45) CYP1A2ALDH1A1L3MBTL1S1PR2S1PR4
SCHEMBL5175881 0.74 ALDH1A1 (0.53) CYP1A2ALDH1A1L3MBTL1EPHX1S1PR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4960771-A TRANSDERMAL DELIVERY OF THERAPEUTIC AGENTS; DRUGS, SUNSCREENS, INSECT REPELLENTS, COSMETICS LVMH MOET HENNESSY LOUIS VUITTON, INC. 1990-10-02 US disclosed
EP-0378657-A1 OXAZOLIDINONE PENETRATION ENHANCING COMPOUNDS. RAJADHYAKSHA VITHAL J 1990-07-25 EP disclosed
WO-1990000407-A1 OXAZOLIDINONE PENETRATION ENHANCING COMPOUNDS RAJADHYAKSHA VITHAL J (US) 1990-01-25 WO disclosed