Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48439 | 0.81 | GAA (0.52) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL5466428 | 0.79 | KDM4E (0.55) | ALDH1A1HSD17B10TSHRKDM4EMAPK1 | |
| SCHEMBL50331 | 0.78 | CYP1A2 (0.53) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL27629506 | 0.77 | CYP1A2 (0.47) | GAAMGAMSIMGAM2NR1I2 | |
| SCHEMBL1619699 | 0.75 | NR1I2 (0.52) | GAAMGAMSIMGAM2NR1I2 | |
| SCHEMBL11783978 | 0.75 | KDM4E (0.59) | GAACYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL10077282 | 0.75 | GAA (0.45) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL15537560 | 0.74 | ALDH1A1 (0.57) | GAAMGAMSIMGAM2NR1I2 | |
| SCHEMBL9791806 | 0.74 | CYP1A2 (0.47) | GAAMGAMSIMGAM2NR1I2 | |
| SCHEMBL6936689 | 0.73 | GAA (0.46) | GAAMGAMSIMGAM2NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0218206-B1 | DISAZO PIGMENTS HAVING A PIPERAZINE BRIDGING MEMBER | BASF Aktiengesellschaft (DE) | 1990-02-07 | — | — | EP | disclosed |