Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8394535 | 1.00 | GBA1 (0.43) | GBA1MEN1KMT2APTGER4PTGER3 | |
| SCHEMBL3636070 | 0.87 | MEN1 (0.43) | GBA1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL10337489 | 0.86 | KMT2A (0.45) | GBA1MEN1KMT2AALDH1A1NAAA | |
| SCHEMBL20733168 | 0.84 | GBA1 (0.44) | GBA1MEN1KMT2APOLBMAPT | |
| SCHEMBL8392269 | 0.83 | MEN1 (0.42) | GBA1MEN1KMT2AALDH1A1NAAA | |
| SCHEMBL20733170 | 0.76 | GBA1 (0.45) | GBA1POLBMAPTNPSR1NAAA | |
| SCHEMBL3514840 | 0.75 | MEN1 (0.36) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6064310 | 0.74 | GBA1 (0.41) | GBA1MEN1KMT2APTGER4PTGER3 | |
| SCHEMBL18640661 | 0.72 | GBA1 (0.41) | GBA1ALDH1A1POLBMAPTNPSR1 | |
| SCHEMBL9323763 | 0.72 | CYP1A2 (0.38) | MEN1KMT2AALDH1A1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378657-A1 | OXAZOLIDINONE PENETRATION ENHANCING COMPOUNDS. | RAJADHYAKSHA VITHAL J | 1990-07-25 | — | — | EP | disclosed |
| WO-1990000407-A1 | OXAZOLIDINONE PENETRATION ENHANCING COMPOUNDS | RAJADHYAKSHA VITHAL J (US) | 1990-01-25 | — | — | WO | disclosed |