Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | MGLL | Q99685 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | EBP | Q15125 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6289681 | 0.88 | GBA1 (0.36) | GBA1GAAABL1RIN1TDP1 | |
| SCHEMBL6289582 | 0.85 | GAA (0.36) | GBA1GAAABL1RIN1TDP1 | |
| SCHEMBL14749807 | 0.85 | PER2 (0.37) | GAAABL1RIN1TDP1TP53 | |
| SCHEMBL9803351 | 0.85 | PER2 (0.37) | GAAABL1RIN1TDP1TP53 | |
| SCHEMBL6284301 | 0.84 | PER2 (0.36) | GBA1MAPT | |
| SCHEMBL6289660 | 0.83 | GAA (0.36) | GBA1GAAABL1RIN1TDP1 | |
| SCHEMBL6287251 | 0.82 | CYP2C19 (0.34) | GBA1 | |
| SCHEMBL6287627 | 0.82 | PER2 (0.36) | GBA1GAAABL1RIN1TDP1 | |
| SCHEMBL6284536 | 0.81 | ACHE (0.32) | SIGMAR1 | |
| SCHEMBL20733168 | 0.81 | GBA1 (0.44) | GBA1GAAABL1RIN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200361910-A1 | PROCESS TO PREPARE PROPYLENE AMINES AND PROPYLENE AMINE DERIVATIVES | NOURYON CHEMICALS INTERNATIONAL B.V. (NL) | 2020-11-19 | — | — | US | disclosed |
| WO-2019030197-A1 | PROCESS TO PREPARE PROPYLENE AMINES AND PROPYLENE AMINE DERIVATIVES | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2019-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200361910-A1 | PROCESS TO PREPARE PROPYLENE AMINES AND PROPYLENE AMINE DERIVATIVES | HRH3, HRH4, HRH1 | GBA1 4083/4885GAA 4803/4885ABL1 2398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.