Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.32 |
| ▸ | MAOA | P21397 | 6/20 | 0.32 |
| ▸ | MAOB | P27338 | 6/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10337718 | 0.90 | KDM1A (0.35) | KDM1AMAOAMAOB | |
| SCHEMBL10337714 | 0.87 | SLC10A2 (0.32) | KDM1AMAOAMAOB | |
| SCHEMBL10337647 | 0.85 | CHRM3 (0.32) | — | |
| SCHEMBL10337530 | 0.85 | CHRM3 (0.32) | — | |
| SCHEMBL10337760 | 0.85 | CHRM3 (0.32) | — | |
| SCHEMBL10337698 | 0.85 | CHRM3 (0.32) | — | |
| SCHEMBL10337739 | 0.85 | CHRM3 (0.32) | — | |
| SCHEMBL10337527 | 0.81 | — | — | |
| SCHEMBL4798663 | 0.80 | HRH3 (0.34) | KDM1AMAOAMAOB | |
| SCHEMBL10337805 | 0.79 | OPRM1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381728-A1 | DIFLUOROMETHYL COMPOUNDS. | MERCK PATENT GMBH (DE) | 1990-08-16 | — | — | EP | disclosed |
| WO-1990001056-A1 | DIFLUOROMETHYL COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-02-08 | — | — | WO | disclosed |