SCHEMBL10337908

CC(C)CNC(=O)C(N)[C@@H](O)[C@H](CC1CCCCC1)C(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)C1Cc2ccccc2O1

nearest known ligand 0.44

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	PSMB5	P28074	6/20	0.44

▸	REN	P00797	10/20	0.43

▸	PSEN1	P49768	1/20	0.40

▸	PSEN2	P49810	1/20	0.40

▸	APH1B	Q8WW43	1/20	0.40

▸	NCSTN	Q92542	1/20	0.40

▸	APH1A	Q96BI3	1/20	0.40

▸	PSENEN	Q9NZ42	1/20	0.40

▸	CTSD	P07339	2/20	0.40

▸	MMP3	P08254	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL10444533	0.82	REN (0.54)	RENPSEN1PSEN2APH1BNCSTN
SCHEMBL10444535	0.82	REN (0.54)	RENPSEN1PSEN2APH1BNCSTN
SCHEMBL10337907	0.82	CTSD (0.37)	PSMB5RENCTSDMMP3
Water SCHEMBL10444629	0.82	REN (0.54)	RENPSEN1PSEN2APH1BNCSTN
SCHEMBL10444220	0.80	REN (0.45)	RENPSEN1PSEN2APH1BNCSTN
SCHEMBL10444137	0.77	MME (0.52)	PSMB5
SCHEMBL10443912	0.77	MME (0.52)	PSMB5
SCHEMBL10443729	0.76	REN (0.43)	RENPSEN1PSEN2APH1BNCSTN
SCHEMBL10444067	0.76	REN (0.51)	RENMMP3
SCHEMBL10444647	0.75	REN (0.43)	PSMB5RENPSEN1PSEN2APH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
JP-2036169-A	—	—	None	—	—	JP	disclosed
JP-H0236169-A	NEW COMPOUND ITS PRODUCTION AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME	BEECHAM GROUP PLC	1990-02-06	—	—	JP	disclosed