Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8849439 | 0.86 | TSHR (0.42) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL69841 | 0.77 | TSHR (0.47) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL11737653 | 0.76 | TSHR (0.46) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL9580885 | 0.75 | THRB (0.34) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL10917669 | 0.74 | AMPD2 (0.36) | TSHRALDH1A1HSD17B10HPGDCYP3A4 | |
| SCHEMBL69828 | 0.73 | TSHR (0.43) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL10592807 | 0.72 | TSHR (0.36) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL225587 | 0.71 | TSHR (0.34) | TSHRHPGD | |
| SCHEMBL11527663 | 0.71 | TSHR (0.47) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL69433 | 0.70 | TSHR (0.37) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2049767-A | — | — | None | — | — | JP | disclosed |
| JP-H0249767-A | UNSATURATED DERIVATIVE OF 2,2,6,6-TETRAMETHYLPIPERIDINE, AND USE THEREOF AS LIGHT STABILIZER AND CROSSLINKING AGENT | CIBA GEIGY AG | 1990-02-20 | — | — | JP | disclosed |