1,3-Butanediol

1,3-Butanediol

SCHEMBL10338243

CC(O)CCO.c1ccc(COCc2ccccc2)cc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.56
CA1 P00915 3/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
KMT2A Q03164 1/20 0.45
KDM4E B2RXH2 1/20 0.43
POLB P06746 1/20 0.43
HTT P42858 2/20 0.42
ALDH1A1 P00352 2/20 0.42
LMNA P02545 2/20 0.42
HPGD P15428 1/20 0.42
MAPK1 P28482 1/20 0.42
TRPA1 O75762 2/20 0.41
NPC1 O15118 1/20 0.40
ALOX5 P09917 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propylene Glycol SCHEMBL5533372 0.86 TSHR (0.62) TSHRCA1CA2CA7CA9
Isopropyl Alcohol SCHEMBL29076646 0.84 TSHR (0.71) TSHRCA1CA2CA7CA9
SCHEMBL20582042 0.83 TSHR (0.52) TSHRCA1CA2CA7CA9
SCHEMBL4781157 0.83 TSHR (0.52) TSHRCA1CA2CA7CA9
SCHEMBL2717727 0.83 TSHR (0.52) TSHRCA1CA2CA7CA9
Benzyl Alcohol SCHEMBL29091766 0.82 TSHR (0.58) TSHRKDM4EPOLBLMNATRPA1
Propylene Glycol SCHEMBL4110602 0.80 TSHR (0.48) TSHRCA1CA2CA7CA9
Propylene Glycol SCHEMBL15618691 0.80 TSHR (0.54) TSHRCA1CA2CA7CA9
SCHEMBL1195445 0.80 CA1 (0.50) TSHRCA1CA2CA7CA9
SCHEMBL542039 0.80 TSHR (0.48) TSHRCA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2039899-A None JP disclosed
JP-H0239899-A PRODUCTION OF OPTICALLY ACTIVE 1,3-BUTANEDIOL 1-BENZYL ETHER AND DERIVATIVE THEREOF DAICEL CHEM IND LTD 1990-02-08 JP disclosed