Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL15618691 | 0.93 | TSHR (0.54) | TSHRCA1CA2CA7CA9 | |
| Isopropyl Alcohol SCHEMBL29076646 | 0.89 | TSHR (0.71) | TSHRCA1CA2CA7CA9 | |
| Propylene Glycol SCHEMBL4110602 | 0.89 | TSHR (0.48) | TSHRCA1CA2CA7CA9 | |
| 1,3-Butanediol SCHEMBL10338243 | 0.86 | TSHR (0.56) | TSHRCA1CA2CA7CA9 | |
| Propylene Glycol SCHEMBL7058411 | 0.86 | TRPA1 (0.47) | TSHRCA1CA2CA7CA9 | |
| Glycerin SCHEMBL3807616 | 0.85 | TSHR (0.65) | TSHRCA1CA2CA7CA9 | |
| Propylene Glycol SCHEMBL4110600 | 0.84 | TRPA1 (0.46) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL1096291 | 0.83 | CA1 (0.61) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL2181772 | 0.83 | CA1 (0.61) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL873616 | 0.83 | CA1 (0.61) | TSHRCA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11193079-B2 | Glycol ether neo-esters, lubricating oil compositions containing same and processes for making same | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2021-12-07 | — | — | US | claimed |
| US-20200399552-A1 | Glycol Ether Neo-Esters, Lubricating Oil Compositions Containing Same And Processes For Making Same | EXXONMOBIL RES & ENG CO (US) | 2020-12-24 | — | — | US | claimed |
| CN-101548241-B | Low etching photoresist cleaning agent | ANJI MICROELECTRONICS CO LTD | 2012-05-30 | — | — | CN | claimed |
| CN-101529339-B | Low etched photoresist cleaning agent and cleaning method of using same | ANJI MICROELECTRONICS (SHANGHAI) Co.,Ltd. (CN) | 2011-11-30 | — | — | CN | claimed |
| CN-101201556-A | Photoresist detergent with low etching property | ANJI MICROELECTRONICS CO LTD (CN) | 2008-06-18 | — | — | CN | claimed |
| CN-101187787-A | Low etching photoresist cleaning agent and its cleaning method | ANJI MICROELECTRONICS CO LTD (CN) | 2008-05-28 | — | — | CN | claimed |
| US-20070249776-A1 | BLACK-MATRIX BANK COMPOSITION AND METHOD FOR MANUFACTURING BLACK-MATRIX BANKS | ICF TECHNOLOGY CO., LTD. (TW) | 2007-10-25 | — | — | US | claimed |
| US-20060283353-A1 | Ink for color filter | ICF TECHNOLOGY CO., LTD. (TW) | 2006-12-21 | — | — | US | claimed |
| EP-1287100-B1 | BIOCIDAL CLEANER COMPOSITION | JOHNSON & SON INC S C (US) | 2006-11-29 | — | — | EP | claimed |
| US-6812196-B2 | FOR REDUCING BIOFILM-ASSOCIATED MICROORGANISMS ON A SURFACE | S.C. JOHNSON & SON, INC. | 2004-11-02 | — | — | US | claimed |
| US-20030083219-A1 | Biocidal cleaner composition containing acid-anionic surfactant-alcohol combinations and method of using the composition | S.C. JOHNSON & SONS, INC. | 2003-05-01 | — | — | US | claimed |
| EP-1287100-A1 | BIOCIDAL CLEANER COMPOSITION | S. C. Johnson & Son, Inc. (US) | 2003-03-05 | — | — | EP | claimed |
| WO-2001094513-A1 | BIOCIDAL CLEANER COMPOSITION | S. C. JOHNSON & SON, INC. (US) | 2001-12-13 | — | — | WO | claimed |
| EP-4400914-B1 | COMPOSITION FOR FORMING RESIST UNDERLAYER FILM, PATTERNING PROCESS, AND METHOD FOR FORMING RESIST UNDERLAYER FILM | SHINETSU CHEMICAL CO (JP) | 2025-12-17 | — | — | EP | disclosed |
| EP-4606882-A1 | CLEANING SOLUTION, METHOD FOR CLEANING SUBSTRATE, AND METHOD FOR FORMING METAL-CONTAINING FILM | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2025-08-27 | — | — | EP | disclosed |
| EP-4607281-A2 | METHOD FOR FORMING ORGANIC FILM AND METHOD FOR MANUFACTURING SUBSTRATE FOR SEMICONDUCTOR DEVICE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2025-08-27 | — | — | EP | disclosed |
| US-20060283353-A1 | Ink for color filter | ICF TECHNOLOGY CO., LTD. (TW) | 2006-12-21 | — | — | US | disclosed |
| US-5723250-A | Process for image formation using liquid developer | FUJI XEROX CO., LTD. (JP) | 1998-03-03 | — | — | US | disclosed |
| US-5622804-A | COMPOSITION INCLUDING CARRIER COMPRISING ETHER COMPOUND, CHARGE DIRECTOR, DISPERSED TONER PARTICLES COMPRISING INSOLUBLE THERMOPLASTIC RESIN, COLORANT, CHARGE CONTROL AGENT | FUJI XEROX CO., LTD. (JP) | 1997-04-22 | — | — | US | disclosed |
| US-5352557-A | Ether compound as carrier liquid | FUJI XEROX CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11193079-B2 | Glycol ether neo-esters, lubricating oil compositions containing same and processes for making same | ELOVL5, ELOVL1, NAPEPLD | TSHR 4502/4885CA1 2792/4885CA2 4715/4885 |
| US-20200399552-A1 | Glycol Ether Neo-Esters, Lubricating Oil Compositions Containing Same And Processes For Making Same | ELOVL5, ELOVL1, NAPEPLD | TSHR 4502/4885CA1 2792/4885CA2 4715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.