Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TLR4 | O00206 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 4/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | CASP1 | P29466 | 3/20 | 0.31 |
| ▸ | CASP7 | P55210 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 3/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10338350 | 1.00 | KCNH2 (0.36) | KCNH2TLR4MAPTKDM4EALDH1A1 | |
| SCHEMBL10701200 | 0.73 | MAPT (0.37) | KCNH2TLR4MAPTKDM4EALDH1A1 | |
| SCHEMBL12998011 | 0.63 | TLR4 (0.40) | KCNH2TLR4KDM4EALDH1A1GAA | |
| SCHEMBL30989570 | 0.63 | KCNH2 (0.44) | KCNH2TLR4KDM4EALDH1A1GAA | |
| SCHEMBL4384894 | 0.62 | KDM4E (0.36) | KCNH2TLR4MAPTKDM4EALDH1A1 | |
| SCHEMBL8267251 | 0.62 | KCNH2 (0.36) | KCNH2TLR4KDM4EPTPN1HPGD | |
| SCHEMBL5798986 | 0.61 | — | — | |
| SCHEMBL20383513 | 0.61 | ALDH1A1 (0.47) | KCNH2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL2834961 | 0.61 | ALDH1A1 (0.47) | KCNH2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL23417814 | 0.61 | KCNH2 (0.41) | KCNH2TLR4KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2059565-A | — | — | None | — | — | JP | disclosed |
| JP-H0259565-A | OPTICALLY ACTIVE OLEFIN LACTONE DERIVATIVE AND PRODUCTION THEREOF | TAKASAGO INTERNATL CORP | 1990-02-28 | — | — | JP | disclosed |