Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 6/20 | 0.36 |
| ▸ | GLA | P06280 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | CASP1 | P29466 | 5/20 | 0.36 |
| ▸ | CASP7 | P55210 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TLR4 | O00206 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10701200 | 0.81 | MAPT (0.37) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL30893395 | 0.74 | ATM (0.40) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL1844172 | 0.74 | GAA (0.40) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL363396 | 0.66 | — | — | |
| SCHEMBL836656 | 0.66 | — | — | |
| SCHEMBL7294823 | 0.65 | LMNA (0.35) | KDM4EALDH1A1GAAHSD17B10TSHR | |
| SCHEMBL9258011 | 0.63 | — | — | |
| SCHEMBL9285114 | 0.63 | — | — | |
| SCHEMBL10338350 | 0.62 | KCNH2 (0.36) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL10338352 | 0.62 | KCNH2 (0.36) | KDM4EALDH1A1GAAGLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667967-B1 | PROCESS FOR PREPARING 2-OXO-1-PYRROLIDINE DERIVATIVES | UCB PHARMA SA (BE) | 2012-08-01 | — | — | EP | disclosed |
| EP-1667967-B1 | PROCESS FOR PREPARING 2-OXO-1-PYRROLIDINE DERIVATIVES | UCB PHARMA SA (BE) | 2012-08-01 | — | — | EP | disclosed |
| US-7629474-B2 | Process for preparing 2-oxo-1-pyrrolidine derivatives | UCB PHARMA S.A. (BE) | 2009-12-08 | — | — | US | disclosed |
| US-7629474-B2 | Process for preparing 2-oxo-1-pyrrolidine derivatives | UCB PHARMA S.A. (BE) | 2009-12-08 | — | — | US | disclosed |
| US-7629474-B2 | Process for preparing 2-oxo-1-pyrrolidine derivatives | UCB PHARMA S.A. (BE) | 2009-12-08 | — | — | US | disclosed |
| US-20070100150-A1 | Process for preparing 2-oxo-1-pyrrolidine derivatives | UCB, S.A. (BE) | 2007-05-03 | — | — | US | disclosed |
| US-20070100150-A1 | Process for preparing 2-oxo-1-pyrrolidine derivatives | UCB, S.A. (BE) | 2007-05-03 | — | — | US | disclosed |
| US-20070100150-A1 | Process for preparing 2-oxo-1-pyrrolidine derivatives | UCB, S.A. (BE) | 2007-05-03 | — | — | US | disclosed |
| EP-1667967-A1 | PROCESS FOR PREPARING 2-OXO-1-PYRROLIDINE DERIVATIVES | UCB, S.A. (BE) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005028435-A1 | PROCESS FOR PREPARING 2-OXO-1-PYRROLIDINE DERIVATIVES | UCB, S.A. (BE) | 2005-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070100150-A1 | Process for preparing 2-oxo-1-pyrrolidine derivatives | PPOX, ODC1, OGDH | KDM4E 803/4885ALDH1A1 179/4885GAA 663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.