SCHEMBL10338587

SCHEMBL10338587

CCOc1cc(N(CC)CC)ccc1/C=N/N(Cc1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.50
ALDH1A1 P00352 9/20 0.50
MEN1 O00255 6/20 0.50
KMT2A Q03164 6/20 0.50
GAA P10253 5/20 0.50
KDM4E B2RXH2 3/20 0.50
POLB P06746 2/20 0.50
MAPK1 P28482 5/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
HTT P42858 1/20 0.48
MCL1 Q07820 1/20 0.48
LMNA P02545 5/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
ATM Q13315 1/20 0.47
PKM P14618 1/20 0.44
HSP90AA1 P07900 1/20 0.43
BACE1 P56817 1/20 0.42
RAB9A P51151 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
CNR2 P34972 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10338588 1.00 MAPT (0.50) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL10338602 0.90 MAPT (0.56) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL10338601 0.90 MAPT (0.56) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL1702513 0.84 MAPT (0.67) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL1702511 0.84 MAPT (0.67) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL8198017 0.79 MAPT (0.62) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL8198016 0.79 MAPT (0.62) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL11751855 0.77 ALDH1A1 (0.51) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL14001820 0.77 CA12 (0.48) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL10704830 0.76 MAPT (0.57) MAPTALDH1A1MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2086637-A None JP disclosed
JP-H0286637-A POLYMERIZABLE RESIN COMPOSITION HITACHI CHEM CO LTD 1990-03-27 JP disclosed