Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10339002 | 1.00 | LMNA (0.58) | LMNAHPGDHTTMAPTKDM4E | |
| SCHEMBL8828561 | 0.89 | LMNA (0.61) | LMNAHPGDHTTMAPTKDM4E | |
| SCHEMBL8828185 | 0.87 | KDM4E (0.66) | LMNAHPGDHTTMAPTKDM4E | |
| SCHEMBL8828303 | 0.87 | HPGD (0.61) | LMNAHPGDHTTMAPTKDM4E | |
| SCHEMBL8828333 | 0.85 | MAPT (0.58) | LMNAHPGDHTTMAPTKDM4E | |
| SCHEMBL8828302 | 0.84 | LMNA (0.58) | LMNAHPGDHTTMAPTKDM4E | |
| SCHEMBL10339004 | 0.84 | LMNA (0.53) | LMNAHPGDHTTMAPTKDM4E | |
| SCHEMBL8828259 | 0.84 | MAPT (0.62) | LMNAHPGDHTTMAPTKDM4E | |
| SCHEMBL9467849 | 0.83 | KDM4E (0.61) | LMNAHPGDHTTMAPTKDM4E | |
| SCHEMBL8828165 | 0.83 | MAPT (0.63) | LMNAHPGDHTTMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2138161-A | — | — | None | — | — | JP | disclosed |
| JP-H02138161-A | SUBSTITUTED CINNAMAMIDE DERIVATIVE | MITSUBISHI KASEI CORP | 1990-05-28 | — | — | JP | disclosed |