Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | P4HB | P07237 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828430 | 0.90 | MAPT (0.59) | LMNAHPGDHTTMAPTALDH1A1 | |
| SCHEMBL8828332 | 0.88 | OPRM1 (0.47) | LMNAHPGDHTTMAPTALDH1A1 | |
| SCHEMBL8828185 | 0.87 | KDM4E (0.66) | LMNAHPGDHTTMAPTALDH1A1 | |
| SCHEMBL8828303 | 0.87 | HPGD (0.61) | LMNAHPGDHTTMAPTALDH1A1 | |
| SCHEMBL8828561 | 0.87 | LMNA (0.61) | LMNAHPGDHTTMAPTALDH1A1 | |
| SCHEMBL10339002 | 0.84 | LMNA (0.58) | LMNAHPGDHTTMAPTALDH1A1 | |
| SCHEMBL10339003 | 0.84 | LMNA (0.58) | LMNAHPGDHTTMAPTALDH1A1 | |
| SCHEMBL9467849 | 0.83 | KDM4E (0.61) | LMNAHPGDHTTMAPTALDH1A1 | |
| SCHEMBL8828333 | 0.83 | MAPT (0.58) | LMNAHPGDHTTMAPTALDH1A1 | |
| SCHEMBL8828183 | 0.83 | MAPT (0.63) | LMNAHPGDHTTMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607953-A | ANTIISCHEMIC AGENTS | EISAI CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| US-5382595-A | Antiischemic agents | EISAI CO., LTD. (JP) | 1995-01-17 | — | — | US | disclosed |
| US-5177089-A | Antiischemic agent, vasodilator | EISAI CO., LTD. (JP) | 1993-01-05 | — | — | US | disclosed |