Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | GAA | P10253 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8027655 | 0.82 | TRPV1 (0.57) | KMT2AGAAMEN1HPGDHTT | |
| SCHEMBL9400389 | 0.81 | NPC1 (0.66) | KMT2AGAAMEN1HPGDNPC1 | |
| SCHEMBL11550498 | 0.80 | ALDH1A1 (0.65) | KMT2AGAAMEN1HPGDNPC1 | |
| SCHEMBL10447471 | 0.80 | TP53 (0.67) | KMT2AGAAMEN1HPGDNPC1 | |
| SCHEMBL8030732 | 0.78 | IDO1 (0.67) | KMT2AMEN1HPGDHTTMAPT | |
| SCHEMBL7723381 | 0.77 | GAA (0.59) | KMT2AGAAMEN1HPGDNPC1 | |
| SCHEMBL1549839 | 0.76 | NPC1 (0.63) | KMT2AGAAMEN1HPGDNPC1 | |
| SCHEMBL29473469 | 0.76 | NPC1 (0.63) | KMT2AGAAMEN1HPGDNPC1 | |
| SCHEMBL20332450 | 0.76 | TSHR (0.70) | KMT2AGAAMEN1HPGDNPC1 | |
| SCHEMBL14577684 | 0.76 | KDM4E (0.63) | KMT2AMEN1HPGDNPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2194019-A | — | — | None | — | — | JP | disclosed |
| JP-H02194019-A | FLAME-RESISTANT POLYCARBONATE AND ITS PRODUCTION | ENICHEM TECNORESINE SPA | 1990-07-31 | — | — | JP | disclosed |
| US-4026940-A | CLEAVING TERT-BUTYL ESTER WITH STRONG ACID | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-05-31 | — | — | US | disclosed |
| US-3954826-A | ANTIBACTERIAL INTERMEDIATES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-05-04 | — | — | US | disclosed |