Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | CTSV | O60911 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | CTSC | P53634 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CTSH | P09668 | 1/20 | 0.32 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11503080 | 0.93 | LTA4H (0.43) | HRH1SLC6A2SLC6A3SLC6A4LTA4H | |
| SCHEMBL4371441 | 0.88 | HRH1 (0.44) | HRH1SLC6A2SLC6A3SLC6A4DDB1 | |
| SCHEMBL15740993 | 0.85 | HRH1 (0.42) | HRH1SLC6A2SLC6A3SLC6A4DDB1 | |
| SCHEMBL15740987 | 0.85 | HRH1 (0.42) | HRH1SLC6A2SLC6A3SLC6A4DDB1 | |
| SCHEMBL15740991 | 0.85 | HRH1 (0.42) | HRH1SLC6A2SLC6A3SLC6A4DDB1 | |
| SCHEMBL27768223 | 0.78 | CHRNB4 (0.42) | ALDH1A1 | |
| SCHEMBL10546701 | 0.75 | SLC6A2 (0.47) | HRH1SLC6A2SLC6A3SLC6A4DDB1 | |
| SCHEMBL9146008 | 0.73 | — | — | |
| SCHEMBL19822418 | 0.72 | LMNA (0.46) | SLC6A2SLC6A3LTA4HCYP2C19 | |
| SCHEMBL18404195 | 0.72 | HRH1 (0.40) | HRH1SLC6A2SLC6A3SLC6A4DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2200652-A | — | — | None | — | — | JP | disclosed |
| JP-H02200652-A | 3-PHENOXYCYCLOPENTENE DERIVATIVE, PREPARATION THEREOF AND PREPARATION OF CYCLOPENTA(B)BENZOFURAN DERIVATIVE FROM THE SAME DERIVATIVE | TORAY IND INC | 1990-08-08 | — | — | JP | disclosed |
| EP-0127143-B1 | NOVEL ARYLOXYCYCLOALKANOLAMINOALKYLENE ARYL KETONES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-03-21 | — | — | EP | disclosed |
| US-4868315-A | HYPOTENSIVE AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-09-19 | — | — | US | disclosed |
| US-4745222-A | HYPOTENSIVE AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-05-17 | — | — | US | disclosed |
| EP-0127143-A2 | Novel aryloxycycloalkanolaminoalkylene aryl ketones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-12-05 | — | — | EP | disclosed |