Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14169706 | 1.00 | TSHR (0.42) | TSHRALDH1A1MAPK1ANPEPKISS1R | |
| SCHEMBL10195414 | 0.94 | — | — | |
| SCHEMBL11890327 | 0.94 | — | — | |
| SCHEMBL106791 | 0.94 | — | — | |
| SCHEMBL13317542 | 0.87 | TSHR (0.44) | TSHRALDH1A1 | |
| SCHEMBL17642229 | 0.87 | TSHR (0.39) | TSHRALDH1A1MAPK1ANPEPKISS1R | |
| SCHEMBL13900281 | 0.84 | — | — | |
| SCHEMBL22456 | 0.84 | TSHR (0.41) | TSHRALDH1A1MAPK1ANPEPKISS1R | |
| SCHEMBL16280840 | 0.84 | — | — | |
| SCHEMBL7516446 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407963-B | Catalyst component for olefin polymerization and preparation method thereof | 中国石油化工股份有限公司 | 2021-09-21 | — | — | CN | claimed |
| CN-110407964-B | Catalyst component for olefin polymerization and preparation method thereof | 中国石油化工股份有限公司 | 2021-09-21 | — | — | CN | claimed |
| CN-110407964-A | Catalyst component for olefin and preparation method thereof | CHINA PETROLEUM & CHEM CORP | 2019-11-05 | — | — | CN | claimed |
| CN-104177520-B | It is used to prepare the ingredient of solid catalyst of olefin polymer | 中国石油化工股份有限公司 | 2018-06-12 | — | — | CN | claimed |
| JP-2225430-A | — | — | None | — | — | JP | disclosed |
| CN-110407964-B | Catalyst component for olefin polymerization and preparation method thereof | 中国石油化工股份有限公司 | 2021-09-21 | — | — | CN | disclosed |
| CN-110407963-B | Catalyst component for olefin polymerization and preparation method thereof | 中国石油化工股份有限公司 | 2021-09-21 | — | — | CN | disclosed |
| US-20170298058-A1 | HETEROCYCLIC RING AND CARBOCYCLIC DERIVATIVE | SHIONOGI & CO (JP) | 2017-10-19 | — | — | US | disclosed |
| US-9550763-B2 | Heterocyclic ring and carbocyclic derivative | SHIONOGI & CO., LTD. (JP) | 2017-01-24 | — | — | US | disclosed |
| US-20160024072-A1 | Heterocyclic Ring and Carbocyclic Derivative | SHIONOGI & CO., LTD. (JP) | 2016-01-28 | — | — | US | disclosed |
| JP-H02225430-A | NOVEL OPTICALLY ACTIVE COMPOUND | WAKO PURE CHEM IND LTD | 1990-09-07 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298058-A1 | HETEROCYCLIC RING AND CARBOCYCLIC DERIVATIVE | P2RX3, P2RX7, P2RX2 | TSHR 737/4885ALDH1A1 2515/4885MAPK1 2105/4885 |
| US-20160024072-A1 | Heterocyclic Ring and Carbocyclic Derivative | P2RX3, P2RX7, P2RX2 | TSHR 737/4885ALDH1A1 2515/4885MAPK1 2105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.