Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 8/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50264 | 0.82 | TDP1 (0.79) | ALDH1A1PKMLMNAGAATDP1 | |
| SCHEMBL20677146 | 0.82 | TDP1 (0.79) | ALDH1A1PKMLMNAGAATDP1 | |
| SCHEMBL21094081 | 0.82 | TDP1 (0.79) | ALDH1A1PKMLMNAGAATDP1 | |
| SCHEMBL7924153 | 0.81 | ALDH1A1 (0.54) | ALDH1A1PKMLMNAGAATDP1 | |
| SCHEMBL11712485 | 0.77 | TDP1 (0.61) | ALDH1A1PKMLMNAGAATDP1 | |
| SCHEMBL21202704 | 0.76 | TDP1 (0.70) | ALDH1A1PKMLMNAGAATDP1 | |
| SCHEMBL1170566 | 0.76 | TDP1 (0.70) | ALDH1A1PKMLMNAGAATDP1 | |
| SCHEMBL14088749 | 0.76 | TDP1 (0.70) | ALDH1A1PKMLMNAGAATDP1 | |
| SCHEMBL19813836 | 0.76 | TDP1 (0.70) | ALDH1A1PKMLMNAGAATDP1 | |
| SCHEMBL2720991 | 0.76 | TDP1 (0.70) | ALDH1A1PKMLMNAGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2240080-A | — | — | None | — | — | JP | disclosed |
| JP-H02240080-A | ISOCYANURATE DERIVATIVE | ASAHI DENKA KOGYO KK | 1990-09-25 | — | — | JP | disclosed |