Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29133152 | 0.84 | NPC1 (0.45) | MAPTTP53POLBUSP2KDM4E | |
| SCHEMBL14363614 | 0.77 | HSP90AA1 (0.49) | MAPTTP53THRBKDM4EHSD17B10 | |
| SCHEMBL23082892 | 0.74 | SMN1; SMN2 (0.58) | MAPTPOLBKDM4EHSD17B10NPC1 | |
| SCHEMBL14363618 | 0.74 | THRB (0.56) | MAPTTP53THRBKDM4EHSD17B10 | |
| SCHEMBL12717346 | 0.73 | MAPT (0.46) | MAPTTP53KDM4EHSD17B10NPSR1 | |
| SCHEMBL24921602 | 0.72 | HDAC1 (0.40) | MAPTTP53POLBUSP2KDM4E | |
| SCHEMBL1250902 | 0.72 | SMN1; SMN2 (0.67) | MAPTTP53POLBKDM4EHSD17B10 | |
| SCHEMBL14363613 | 0.70 | NPC1 (0.49) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL24921550 | 0.70 | L3MBTL1 (0.38) | MAPTTP53POLBUSP2KDM4E | |
| SCHEMBL5883322 | 0.70 | KDM4E (0.46) | MAPTTP53POLBUSP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2250873-A | — | — | None | — | — | JP | disclosed |
| JP-H02250873-A | 1,2,4-OXADIAZOLE DERIVATIVE AND HERBICIDE CONTAINING THE SAME DERIVATIVE AS ACTIVE INGREDIENT | MITSUBISHI PETROCHEM CO LTD | 1990-10-08 | — | — | JP | disclosed |