Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6763264 | 0.90 | NOS2 (0.50) | NOS2SKP2TLR8ALDH1A1HTT | |
| SCHEMBL23863705 | 0.88 | NOS2 (0.42) | NOS2SKP2ALDH1A1HTTMAPT | |
| SCHEMBL13890665 | 0.84 | NOS2 (0.46) | NOS2SKP2TLR8ALDH1A1HTT | |
| SCHEMBL7027697 | 0.82 | SKP2 (0.40) | NOS2SKP2TLR8ALDH1A1HTT | |
| SCHEMBL22184100 | 0.81 | MAPT (0.48) | NOS2SKP2ALDH1A1HTTMAPT | |
| SCHEMBL28033920 | 0.78 | NOS2 (0.41) | NOS2SKP2ALDH1A1CYP3A4 | |
| SCHEMBL20788166 | 0.76 | NOS2 (0.47) | NOS2SKP2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL11745408 | 0.76 | SKP2 (0.47) | NOS2SKP2TLR8ALDH1A1HTT | |
| SCHEMBL4455067 | 0.76 | SKP2 (0.52) | NOS2SKP2TLR8ALDH1A1HTT | |
| SCHEMBL12971475 | 0.74 | SKP2 (0.42) | NOS2SKP2TLR8ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2269727-A | — | — | None | — | — | JP | disclosed |
| JP-H02269727-A | PRODUCTION OF POLYURETHANE UREA ELASTOMER AND ITS MOLDING | MITSUI TOATSU CHEM INC | 1990-11-05 | — | — | JP | disclosed |