SCHEMBL28033920

SCHEMBL28033920

CCCCc1cc(C)cc(N)c1OC

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 1/20 0.41
SKP2 Q13309 1/20 0.39
ALOX5 P09917 9/20 0.36
HTR2A P28223 1/20 0.36
ACHE P22303 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
PTGS2 P35354 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28187609 0.87 ACHE (0.41) NOS2ALOX5HTR2AACHEALDH1A1
SCHEMBL27873246 0.81 ALOX5 (0.35) SKP2ALOX5HTR2APTGS2
SCHEMBL24503610 0.79 MAPT (0.39) NOS2ALOX5ACHE
SCHEMBL10339809 0.78 NOS2 (0.46) NOS2SKP2ALDH1A1CYP3A4
SCHEMBL13890665 0.78 NOS2 (0.46) NOS2SKP2ALDH1A1
SCHEMBL6763264 0.75 NOS2 (0.50) NOS2SKP2ALDH1A1
SCHEMBL22184100 0.75 MAPT (0.48) NOS2SKP2ALOX5ALDH1A1CYP3A4
SCHEMBL4621087 0.74 ACHE (0.52) ACHEALDH1A1CYP3A4
SCHEMBL29112783 0.74 NOS2 (0.38) NOS2SKP2ALOX5ALDH1A1PTGS2
SCHEMBL28665185 0.74 NOS2 (0.38) NOS2SKP2ALOX5ALDH1A1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105085576-A Pyridinamine-based chromium complex and preparation method and application thereof UNIV EAST CHINA SCIENCE & TECH 2015-11-25 CN disclosed