Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8607757 | 1.00 | TSHR (0.43) | — | |
| Hydrochloric Acid SCHEMBL21243862 | 1.00 | TSHR (0.43) | — | |
| Hydrochloric Acid SCHEMBL9194226 | 0.96 | TSHR (0.40) | — | |
| SCHEMBL16432 | 0.96 | TSHR (0.46) | — | |
| SCHEMBL29398848 | 0.96 | TSHR (0.46) | — | |
| Hydrochloric Acid SCHEMBL5918591 | 0.92 | — | — | |
| SCHEMBL1230027 | 0.92 | TSHR (0.43) | — | |
| SCHEMBL2997424 | 0.92 | TSHR (0.43) | — | |
| SCHEMBL1230019 | 0.92 | TSHR (0.43) | — | |
| SCHEMBL1229816 | 0.92 | TSHR (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478847-B | Catalyst carrier for olefin polymerization, preparation method and application thereof, catalyst and application thereof | 中国石油化工股份有限公司 | 2023-07-21 | — | — | CN | claimed |
| CN-114478847-A | Catalyst carrier for olefin polymerization, preparation method and application thereof, catalyst and application thereof | 中国石油化工股份有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-114478863-A | Catalyst component for olefin polymerization, preparation method thereof, catalyst and application thereof, polyolefin and preparation method thereof | 中国石油化工股份有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-114478846-A | Carrier of catalyst with function of catalyzing olefin polymerization, preparation method and application of carrier, olefin polymerization catalyst and application of olefin polymerization catalyst | 中国石油化工股份有限公司 | 2022-05-13 | — | — | CN | claimed |
| EP-2276753-A1 | INTERMEDIATES FOR THE PREPARATION OF (3R, 4S) -1- (4-FLUOROPHENYL) -3- [ (3S) -3- (4-FLUOROPHENYL) -3-HYDROXYPROPYL) ] -4- (4-HYDROXYPHENYL) -2-AZETIDINONE | Zentiva, K.S. (CZ) | 2011-01-26 | — | — | EP | claimed |
| WO-2009106021-A1 | INTERMEDIATES FOR THE PREPARATION OF (3R, 4S) -1- (4-FLUOROPHENYL) -3- [ (3S) -3- (4-FLUOROPHENYL) -3-HYDROXYPROPYL) ] -4- (4-HYDROXYPHENYL) -2-AZETIDINONE | ZENTIVA, K.S. (CZ) | 2009-09-03 | — | — | WO | claimed |
| CN-113755112-B | Adhesive sheet, adherend with adhesive sheet, and method for using adhesive sheet | 爱天思株式会社 | 2024-10-18 | — | — | CN | disclosed |
| CN-116041580-B | Silicon-containing spherical olefin polymerization catalyst component, preparation method and catalyst system | 中国石油化工股份有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-118234825-A | Adhesive, laminate, and packaging material | DIC株式会社 | 2024-06-21 | — | — | CN | disclosed |
| CN-118103472-A | Adhesive, laminate, and packaging material | DIC株式会社 | 2024-05-28 | — | — | CN | disclosed |
| CN-114621372-B | Ultra-high molecular weight ethylene homopolymers and process for preparing the same | 中国石油化工股份有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-114507310-B | Ultra-high molecular weight ethylene copolymer and preparation method thereof | 中国石油化工股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-114456288-B | Titanium-containing catalyst, catalyst for olefin polymerization reaction, preparation method and application thereof | 中国石油化工股份有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-101715461-A | Super high molecular weight ethylene-alpha-olefin copolymer powder | SUMITOMO CHEMICAL CO | 2010-05-26 | — | — | CN | disclosed |
| EP-0889060-A1 | Transition metal-magnesium catalyst precursors, catalysts and polymerization processes | Chevron Chemical Company LLC (US) | 1999-01-07 | — | — | EP | disclosed |
| EP-0599355-B1 | Catalysts for polymerization of olefins | CHISSO CORP (JP) | 1996-10-16 | — | — | EP | disclosed |
| EP-0599355-A1 | Catalysts for polymerization of olefins | CHISSO CORPORATION (JP) | 1994-06-01 | — | — | EP | disclosed |
| US-5084429-A | Coordination catalysts for olefin polymerization from magnesium, titanium, vanadium and silicon compounds | CHISSO CORPORATION (JP) | 1992-01-28 | — | — | US | disclosed |
| EP-0415704-A2 | Catalysts for polymerization of olefins | CHISSO CORPORATION (JP) | 1991-03-06 | — | — | EP | disclosed |
| US-4304925-A | ESTERIFYING IN THE PRESENCE OF AN ORGANOMETALLIC CATALYST | SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1981-12-08 | — | — | US | disclosed |