Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 5/20 | 0.35 |
| ▸ | CES1 | P23141 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LSS | P48449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1034009 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL8607757 | 1.00 | TSHR (0.43) | TSHRLMNATHRBCES2CES1 | |
| Hydrochloric Acid SCHEMBL9194226 | 0.96 | TSHR (0.40) | TSHRLMNATHRBCES2CES1 | |
| SCHEMBL16432 | 0.96 | TSHR (0.46) | TSHRLMNATHRBCES2CES1 | |
| SCHEMBL29398848 | 0.96 | TSHR (0.46) | TSHRLMNATHRBCES2CES1 | |
| Hydrochloric Acid SCHEMBL5918591 | 0.92 | — | — | |
| SCHEMBL1230027 | 0.92 | TSHR (0.43) | TSHRLMNATHRBCES2CES1 | |
| SCHEMBL2997424 | 0.92 | TSHR (0.43) | TSHRLMNATHRBCES2CES1 | |
| SCHEMBL1230019 | 0.92 | TSHR (0.43) | TSHRLMNATHRBCES2CES1 | |
| SCHEMBL1229816 | 0.92 | TSHR (0.43) | TSHRLMNATHRBCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122037023-A | Homo-polypropylene and preparation method thereof | 中国石油化工股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-120059153-A | Method and process system for preparing poly (succinate) polyester by taking maleic anhydride and/or derivatives thereof as raw materials | 上海师范大学 | 2025-05-30 | — | — | CN | claimed |
| CN-120059154-A | In C4Method for producing polybutylene succinate polyester by taking unsaturated binary oxygen-containing compound as raw material | 上海师范大学 | 2025-05-30 | — | — | CN | claimed |
| CN-119912605-A | Catalyst component for olefin polymerization and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-05-02 | — | — | CN | claimed |
| CN-119841977-A | Solid catalyst component for olefin polymerization, preparation method thereof, catalyst and application | 中国石油化工股份有限公司 | 2025-04-18 | — | — | CN | claimed |
| CN-119841987-A | Homo-polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-04-18 | — | — | CN | claimed |
| CN-119841976-A | Solid catalyst component for olefin polymerization, preparation method thereof, catalyst and application | 中国石油化工股份有限公司 | 2025-04-18 | — | — | CN | claimed |
| CN-115975084-B | Catalyst component for olefin polymerization, catalyst and application | 中国石油化工股份有限公司 | 2025-02-28 | — | — | CN | claimed |
| CN-115975079-B | Catalyst component for olefin polymerization, catalyst and application | 中国石油化工股份有限公司 | 2025-02-28 | — | — | CN | claimed |
| CN-116023560-B | Polypropylene microsphere, preparation method thereof, 3D printing raw material and application | 中国石油化工股份有限公司 | 2024-09-17 | — | — | CN | claimed |
| CN-116375911-A | Catalyst for olefin polymerization, preparation method thereof and olefin polymerization method | 山东京博石油化工有限公司 | 2023-07-04 | — | — | CN | claimed |
| CN-112759687-B | Catalyst component for olefin polymerization and preparation method thereof, catalyst and olefin polymerization method | 中国石油化工股份有限公司 | 2023-05-12 | — | — | CN | claimed |
| CN-116041586-A | Catalyst component for olefin polymerization, preparation method thereof, catalyst and olefin polymerization method | 中国石油化工股份有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-116041581-A | Olefin polymerization catalyst component, preparation method and application thereof | 中国石油化工股份有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-116023560-A | Polypropylene microsphere, preparation method thereof, 3D printing raw material and application | 中国石油化工股份有限公司 | 2023-04-28 | — | — | CN | claimed |
| CN-116003904-A | Low-VOC (volatile organic compound) ultrahigh-flow high-rigidity impact-resistant polypropylene composition and preparation method thereof | 中国石油化工股份有限公司 | 2023-04-25 | — | — | CN | claimed |
| CN-112759604-B | Magnesium halide adduct and preparation method thereof, catalyst component for olefin polymerization, catalyst and olefin polymerization method | 中国石油化工股份有限公司 | 2022-08-19 | — | — | CN | claimed |
| CN-112759687-A | Catalyst component for olefin polymerization, preparation method thereof, catalyst and olefin polymerization method | 中国石油化工股份有限公司 | 2021-05-07 | — | — | CN | claimed |
| US-10927195-B2 | Olefin coordination polymerization catalyst and use thereof | PETROCHINA COMPANY LIMITED (CN) | 2021-02-23 | — | — | US | claimed |
| US-20190248928-A1 | Olefin Coordination Polymerization Catalyst and Use Thereof | PETROCHINA COMPANY LIMITED (CN) | 2019-08-15 | — | — | US | claimed |