Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10340227 | 1.00 | ALDH1A1 (0.46) | ALDH1A1FKBP1AKMT2AMEN1MAPK1 | |
| SCHEMBL10340224 | 1.00 | ALDH1A1 (0.46) | ALDH1A1FKBP1AKMT2AMEN1MAPK1 | |
| SCHEMBL11483634 | 0.95 | ALDH1A1 (0.44) | ALDH1A1FKBP1AKMT2AMEN1MAPK1 | |
| SCHEMBL2098632 | 0.90 | CHRM4 (0.45) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL14296477 | 0.90 | ALDH1A1 (0.46) | ALDH1A1FKBP1AKMT2AMEN1MAPK1 | |
| SCHEMBL27746599 | 0.88 | ALDH1A1 (0.49) | ALDH1A1KMT2AMAPTPOLBRAB9A | |
| SCHEMBL10560081 | 0.87 | PPM1B (0.38) | — | |
| SCHEMBL23662579 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KMT2AMAPTPOLBRAB9A | |
| SCHEMBL12015491 | 0.83 | KDM4E (0.37) | ALDH1A1FKBP1AKDM4EPOLB | |
| SCHEMBL12015495 | 0.82 | ALDH1A1 (0.36) | ALDH1A1FKBP1AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248824-B1 | USE OF CIS-N-(2 AMINOCYCLOALIPHATIC) BENZENE ACETAMIDE AND BENZAMIDE FOR THE MANUFACTURE OF ANTICONVULSANTS | THE UPJOHN COMPANY (US) | 1990-01-17 | — | — | EP | disclosed |
| US-4801604-A | REDUCED ANALGESIC PROPERTIES | THE UPJOHN COMPANY (US) | 1989-01-31 | — | — | US | disclosed |
| EP-0248824-A1 | Use of CIS-N-(2 Aminocycloaliphatic) benzene acetamide and Benzamide for the manufacture of anticonvulsants. | UPJOHN CO (US) | 1987-12-16 | — | — | EP | disclosed |
| EP-0222533-A1 | Cis-N-[(2-aminocycloaliphatic)benzene acetamide and -benzamide anticonvulsants | THE UPJOHN COMPANY (US) | 1987-05-20 | — | — | EP | disclosed |
| WO-1987002584-A1 | CIS-N-(2-AMINOCYCLOALIPHATIC)BENZENE ACETAMIDE AND -BENZAMIDE ANTICONVULSANTS | THE UPJOHN COMPANY (US) | 1987-05-07 | — | — | WO | disclosed |