SCHEMBL10340290

SCHEMBL10340290

O=c1ncc(F)c[nH]1.OC[C@H]1OC[C@H](O)[C@@H]1O

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.31
DPP8 Q6V1X1 1/20 0.31
DPP9 Q86TI2 1/20 0.31
DPP7 Q9UHL4 1/20 0.31
PRKAG1 P54619 1/20 0.30
PRKAA2 P54646 1/20 0.30
PRKAB1 Q9Y478 1/20 0.30
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10422311 0.85 PNP (0.31)
Ribose (Furanose) SCHEMBL10422255 0.80 PNP (0.38) LMNASMN1; SMN2
Flucytosine SCHEMBL4201130 0.78 ALB (0.32) PRKAG1PRKAA2PRKAB1LMNASMN1; SMN2
SCHEMBL4199979 0.73 PNP (0.32) LMNASMN1; SMN2
Fluorouracil SCHEMBL4289411 0.73 LMNA (0.50) PRKAG1PRKAA2PRKAB1LMNASMN1; SMN2
SCHEMBL309070 0.72
SCHEMBL4198780 0.71
SCHEMBL23273618 0.70
SCHEMBL4420375 0.70
SCHEMBL2621328 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0175004-B1 NOVEL 5-SUBSTITUTED 2-PYRIMIDINONE NUCLEOSIDES AND METHODS OF USE THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1990-01-03 EP disclosed