SCHEMBL10340484

SCHEMBL10340484

CCCCCCCCCCCCNS(=O)(=O)c1ccc([N+]#N)cc1.F[B-](F)(F)F

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.51
PKM P14618 3/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
LMNA P02545 4/20 0.50
HTT P42858 4/20 0.50
MAPK1 P28482 1/20 0.50
SMN1; SMN2 Q16637 5/20 0.46
KDM4E B2RXH2 1/20 0.46
EPHX2 P34913 1/20 0.44
TSHR P16473 2/20 0.44
RECQL P46063 1/20 0.44
CA12 O43570 2/20 0.43
CA9 Q16790 2/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
NPY1R P25929 1/20 0.42
NPY2R P49146 1/20 0.42
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10337341 1.00 ALDH1A1 (0.51) ALDH1A1PKMMEN1KMT2ALMNA
SCHEMBL11120645 0.94 LMNA (0.55) ALDH1A1PKMMEN1KMT2ALMNA
SCHEMBL15077048 0.89 LMNA (0.55) ALDH1A1PKMMEN1KMT2ALMNA
SCHEMBL10337334 0.78 MAPK1 (0.67) ALDH1A1PKMKMT2ALMNAHTT
SCHEMBL634183 0.76 ALDH1A1 (0.72) ALDH1A1PKMMEN1KMT2ALMNA
SCHEMBL223156 0.76 ALDH1A1 (0.72) ALDH1A1PKMMEN1KMT2ALMNA
SCHEMBL7130425 0.76 ALDH1A1 (0.60) ALDH1A1PKMMEN1KMT2ALMNA
SCHEMBL9293542 0.76 LMNA (0.60) ALDH1A1PKMMEN1KMT2ALMNA
SCHEMBL7103280 0.76 ALDH1A1 (0.72) ALDH1A1PKMMEN1KMT2ALMNA
SCHEMBL8355315 0.76 ALDH1A1 (0.72) ALDH1A1PKMMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0158507-B1 REAGENT COMPOSITION, DRY ELEMENT AND METHOD FOR DETERMINATION OF TOTAL BILIRUBIN EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-12-05 EP claimed
EP-0158507-A2 Reagent composition, dry element and method for determination of total bilirubin EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-10-16 EP claimed
EP-0158507-B1 REAGENT COMPOSITION, DRY ELEMENT AND METHOD FOR DETERMINATION OF TOTAL BILIRUBIN EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-12-05 EP disclosed
EP-0158506-B1 METHOD AND APPARATUS FOR DETERMINATION OF AN ANALYTE AND METHOD OF CALIBRATING SUCH APPARATUS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-02-28 EP disclosed
US-4627014-A Chemical analyzer for the determination of an analyte EASTMAN KODAK COMPANY (US) 1986-12-02 US disclosed
EP-0087599-B1 DIAZONIUM SALTS AND REAGENTS FOR BILIRUBIN ASSAY EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1986-11-05 EP disclosed
US-4548905-A Reagent composition, dry element and method for determination of total bilirubin EASTMAN KODAK COMPANY (US) 1985-10-22 US disclosed
EP-0158506-A2 Method and apparatus for determination of an analyte and method of calibrating such apparatus EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-10-16 EP disclosed
EP-0158507-A2 Reagent composition, dry element and method for determination of total bilirubin EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-10-16 EP disclosed
US-4468467-A Diazonium salt for bilirubin assay EASTMAN KODAK COMPANY (US) 1984-08-28 US disclosed
EP-0087599-A1 Diazonium salts and reagents for bilirubin assay EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-09-07 EP disclosed