Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5697352 | 1.00 | TSHR (0.50) | TSHRHSD17B10CNR1CNR2LIPG | |
| SCHEMBL5307030 | 1.00 | TSHR (0.50) | TSHRHSD17B10CNR1CNR2LIPG | |
| SCHEMBL9211839 | 1.00 | TSHR (0.50) | TSHRHSD17B10CNR1CNR2LIPG | |
| SCHEMBL10340506 | 1.00 | TSHR (0.50) | TSHRHSD17B10CNR1CNR2LIPG | |
| SCHEMBL4455682 | 0.99 | TSHR (0.48) | TSHRHSD17B10CNR1CNR2LIPG | |
| SCHEMBL28273598 | 0.94 | ADRA2C (0.44) | TSHRHSD17B10CNR1CNR2ADRA2C | |
| SCHEMBL31512576 | 0.92 | TSHR (0.44) | TSHRHSD17B10CNR1CNR2LIPG | |
| SCHEMBL8376943 | 0.89 | TSHR (0.56) | TSHRHSD17B10CNR1CNR2ADRA2C | |
| SCHEMBL30477373 | 0.88 | ADRA2C (0.47) | ADRA2CPTGDR2CYP19A1KDM4EALDH1A1 | |
| SCHEMBL5925419 | 0.85 | ADRA2C (0.46) | TSHRHSD17B10CNR1CNR2LIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144683-B1 | ALIGNMENT LAYER ORIENTATION IN LIQUID CRYSTAL DISPLAYS | International Business Machines Corporation (US) | 1990-01-03 | — | — | EP | disclosed |