SCHEMBL4455682

SCHEMBL4455682

CCCCCc1cc(C#N)ccc1-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.48
HSD17B10 Q99714 1/20 0.48
ADRA2C P18825 1/20 0.43
CNR1 P21554 1/20 0.43
CNR2 P34972 1/20 0.43
PTGDR2 Q9Y5Y4 1/20 0.41
LIPG Q9Y5X9 1/20 0.41
CYP19A1 P11511 3/20 0.40
CYP11B1 P15538 2/20 0.40
CYP11B2 P19099 2/20 0.40
ABCB1 P08183 1/20 0.39
ABCG2 Q9UNQ0 1/20 0.39
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
GAA P10253 2/20 0.38
HPGD P15428 2/20 0.38
GALR3 O60755 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
APAF1 O14727 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9211839 0.99 TSHR (0.50) TSHRHSD17B10ADRA2CCNR1CNR2
SCHEMBL10340558 0.99 TSHR (0.50) TSHRHSD17B10ADRA2CCNR1CNR2
SCHEMBL5697352 0.99 TSHR (0.50) TSHRHSD17B10ADRA2CCNR1CNR2
SCHEMBL10340506 0.99 TSHR (0.50) TSHRHSD17B10ADRA2CCNR1CNR2
SCHEMBL5307030 0.99 TSHR (0.50) TSHRHSD17B10ADRA2CCNR1CNR2
SCHEMBL28273598 0.95 ADRA2C (0.44) TSHRHSD17B10ADRA2CCNR1CNR2
SCHEMBL31512576 0.93 TSHR (0.44) TSHRHSD17B10ADRA2CCNR1CNR2
SCHEMBL8376943 0.91 TSHR (0.56) TSHRHSD17B10ADRA2CCNR1CNR2
SCHEMBL30477373 0.89 ADRA2C (0.47) ADRA2CPTGDR2CYP19A1CYP11B1CYP11B2
SCHEMBL5925419 0.86 ADRA2C (0.46) TSHRHSD17B10ADRA2CCNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118479749-A Color-changing film composite structure and preparation method thereof 珠海水发兴业新材料科技有限公司 2024-08-13 CN claimed
CN-118169925-A Continuous electrochromic polymer stabilized cholesteric liquid crystal material and preparation method thereof 大连理工大学 2024-06-11 CN claimed
CN-117434772-A PDLC switchable glass and preparation method thereof 安徽菲尔慕材料有限公司 2024-01-23 CN claimed
CN-115981060-A High-shielding-degree electric control dimming color-changing film and preparation method thereof 珠海兴业新材料科技有限公司 2023-04-18 CN claimed
CN-114863791-A Multiple anti-counterfeit label and preparation method thereof 中国科学技术大学 2022-08-05 CN claimed
CN-114686049-A Printing ink with multiple anti-counterfeiting effects and preparation method and application thereof 中国科学技术大学 2022-07-01 CN claimed
EP-1599562-B9 NEMATIC LIQUID CRYSTAL MIXTURES FOR BISTABLE DISPLAY DEVICES NEMOPTIC (FR) 2008-09-24 EP claimed
EP-1599562-B1 NEMATIC LIQUID CRYSTAL MIXTURES FOR BISTABLE DISPLAY DEVICES NEMOPTIC (FR) 2007-05-16 EP claimed
WO-2006032029-A2 ALL-OPTICALLY PREPARED AND CONTROLLED NEMATIC LIQUID CRYSTAL LIGHT VALVE COLORADO SCHOOL OF MINES (US) 2006-03-23 WO claimed
CN-122063798-A Single-layer double-chiral interpenetrating network liquid crystal elastomer grating and preparation method thereof 深圳市唯酷光电有限公司 2026-05-19 CN disclosed
CN-118479749-A Color-changing film composite structure and preparation method thereof 珠海水发兴业新材料科技有限公司 2024-08-13 CN disclosed
CN-118169925-A Continuous electrochromic polymer stabilized cholesteric liquid crystal material and preparation method thereof 大连理工大学 2024-06-11 CN disclosed
CN-118005574-A Chiral luminescent molecule, preparation method thereof and chiral luminescent liquid crystal 深圳市宝安区新材料研究院 2024-05-10 CN disclosed
CN-117925297-A Application of zirconium dioxide in ultra-smooth system 武汉轻工大学 2024-04-26 CN disclosed
EP-0180592-B1 LIGHT MODULATING MATERIAL COMPRISING A LIQUID CRYSTAL DISPERSION IN A SYNTHETIC RESIN MATRIX UNIV KENT STATE OHIO (US) 1995-08-02 EP disclosed
EP-0238626-B1 LIQUID CRYSTAL LIGHT-MODULATING MATERIALS UNIV KENT STATE OHIO (US) 1995-05-03 EP disclosed
EP-0238626-A4 LIQUID CRYSTAL LIGHT-MODULATING MATERIALS. UNIV KENT STATE OHIO (US) 1989-07-26 EP disclosed
EP-0238626-A1 LIQUID CRYSTAL LIGHT-MODULATING MATERIALS. UNIV KENT STATE OHIO (US) 1987-09-30 EP disclosed
WO-1987001822-A1 LIQUID CRYSTAL LIGHT-MODULATING MATERIALS KENT STATE UNIVERSITY (US) 1987-03-26 WO disclosed
WO-1985004262-A1 LIGHT MODULATING MATERIAL COMPRISING A LIQUID CRYSTAL DISPERSION IN A SYNTHETIC RESIN MATRIX KENT STATE UNIVERSITY (US) 1985-09-26 WO disclosed