Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL619244 | 0.72 | CA2 (0.43) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL7770990 | 0.70 | — | — | |
| SCHEMBL8959182 | 0.70 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL7765728 | 0.67 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL24607213 | 0.64 | — | — | |
| SCHEMBL27574608 | 0.64 | — | — | |
| SCHEMBL8822944 | 0.64 | HDAC3 (0.38) | SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL726450 | 0.64 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL9736805 | 0.61 | — | — | |
| SCHEMBL18343317 | 0.61 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237397-B1 | STEROIDS SATURATED IN 9(11) AND SUBSTITUTED IN POSITION 10 BY A RADICAL CONTAINING A TRIPLE BOND, PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1990-02-07 | — | — | EP | claimed |