Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | RPA1 | P27694 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10393453 | 0.86 | RIPK2 (0.42) | PTPN1RIPK2RAB9ATSHRL3MBTL1 | |
| SCHEMBL10340610 | 0.86 | RIPK2 (0.64) | RIPK2RAB9AHPGDL3MBTL1NPC1 | |
| SCHEMBL2868550 | 0.85 | MEN1 (0.49) | PTPN1RAB9AMEN1KMT2AUSP2 | |
| SCHEMBL10340579 | 0.85 | RAB9A (0.50) | RIPK2RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL10340690 | 0.85 | RIPK2 (0.48) | PTPN1RIPK2RAB9AMEN1KMT2A | |
| SCHEMBL10624292 | 0.85 | MAPK14 (0.53) | PTPN1RIPK2L3MBTL1SMN1; SMN2NR4A3 | |
| SCHEMBL10340584 | 0.84 | NOTUM (0.45) | RIPK2RAB9AMEN1KMT2ANPSR1 | |
| SCHEMBL10340538 | 0.84 | HTT (0.51) | RIPK2RAB9AKMT2AL3MBTL1NPC1 | |
| SCHEMBL3374632 | 0.81 | PTPN1 (0.69) | PTPN1RIPK2RAB9AMEN1KMT2A | |
| SCHEMBL10340571 | 0.81 | PTPN1 (0.48) | PTPN1RIPK2RAB9AL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0177242-B1 | POLLEN FORMATION INHIBITING PYRAZOLES | ELI LILLY AND COMPANY (US) | 1990-01-03 | — | — | EP | disclosed |
| US-4775409-A | PREVENTING POLLEN FORMATION | ELI LILLY AND COMPANY (US) | 1988-10-04 | — | — | US | disclosed |
| US-4666504-A | HYBRIDS | ELI LILLY AND COMPANY (US) | 1987-05-19 | — | — | US | disclosed |
| EP-0177242-A2 | Pollen formation inhibiting pyrazoles | ELI LILLY AND COMPANY (US) | 1986-04-09 | — | — | EP | disclosed |