Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10340610 | 0.86 | RIPK2 (0.64) | RIPK2SMN1; SMN2L3MBTL1NR4A3POLB | |
| SCHEMBL10393416 | 0.85 | RIPK2 (0.41) | RIPK2SMN1; SMN2L3MBTL1NR4A3POLB | |
| SCHEMBL10340579 | 0.85 | RAB9A (0.50) | RIPK2SMN1; SMN2L3MBTL1NR4A3POLB | |
| SCHEMBL10340641 | 0.85 | PTPN1 (0.50) | RIPK2SMN1; SMN2L3MBTL1NR4A3POLB | |
| SCHEMBL10624292 | 0.85 | MAPK14 (0.53) | RIPK2SMN1; SMN2L3MBTL1NR4A3POLB | |
| SCHEMBL10340567 | 0.83 | RIPK2 (0.47) | RIPK2SMN1; SMN2L3MBTL1NR4A3POLB | |
| SCHEMBL594205 | 0.81 | RIPK2 (0.58) | RIPK2SMN1; SMN2POLBRAB9ANPC1 | |
| SCHEMBL10621474 | 0.81 | ALKBH5 (0.42) | RIPK2SMN1; SMN2L3MBTL1NR4A3MAPT | |
| SCHEMBL10394150 | 0.79 | MAPK1 (0.37) | RIPK2SMN1; SMN2L3MBTL1NR4A3POLB | |
| SCHEMBL10340571 | 0.78 | PTPN1 (0.48) | RIPK2SMN1; SMN2L3MBTL1NR4A3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0177242-B1 | POLLEN FORMATION INHIBITING PYRAZOLES | ELI LILLY AND COMPANY (US) | 1990-01-03 | — | — | EP | disclosed |
| US-4775409-A | PREVENTING POLLEN FORMATION | ELI LILLY AND COMPANY (US) | 1988-10-04 | — | — | US | disclosed |
| US-4666504-A | HYBRIDS | ELI LILLY AND COMPANY (US) | 1987-05-19 | — | — | US | disclosed |
| EP-0177242-A2 | Pollen formation inhibiting pyrazoles | ELI LILLY AND COMPANY (US) | 1986-04-09 | — | — | EP | disclosed |