Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6314704 | 0.88 | RAB9A (0.59) | HTTALDH1A1HPGDSMN1; SMN2NPBWR1 | |
| SCHEMBL1353689 | 0.86 | HTT (0.77) | HTTALDH1A1HPGDSMN1; SMN2ALOX15 | |
| SCHEMBL31117075 | 0.86 | HTT (0.77) | HTTALDH1A1HPGDSMN1; SMN2ALOX15 | |
| SCHEMBL5069717 | 0.85 | ALDH1A1 (0.71) | HTTALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL10340619 | 0.84 | HTT (0.55) | HTTALDH1A1HPGDSMN1; SMN2NPBWR1 | |
| SCHEMBL10366513 | 0.81 | NPC1 (0.53) | ALDH1A1SMN1; SMN2NPBWR1MCHR1RAB9A | |
| SCHEMBL18490171 | 0.81 | ALDH1A1 (0.45) | HTTALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL18987027 | 0.80 | HTT (0.56) | HTTALDH1A1HPGDSMN1; SMN2NPBWR1 | |
| SCHEMBL18706592 | 0.78 | HTT (0.59) | HTTALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL1195700 | 0.78 | ALDH1A1 (0.57) | HTTALDH1A1HPGDSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1016398-B | The pollen that contains pyrazole derivatives generates composite inhibiting | ELLI LILLY & CO (US) | 1992-04-29 | — | — | CN | disclosed |
| EP-0177242-B1 | POLLEN FORMATION INHIBITING PYRAZOLES | ELI LILLY AND COMPANY (US) | 1990-01-03 | — | — | EP | disclosed |
| US-4775409-A | PREVENTING POLLEN FORMATION | ELI LILLY AND COMPANY (US) | 1988-10-04 | — | — | US | disclosed |
| US-4666504-A | HYBRIDS | ELI LILLY AND COMPANY (US) | 1987-05-19 | — | — | US | disclosed |