Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.33 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.33 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.33 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196718 | 0.73 | CYP3A4 (0.44) | IDO1CA1CA2CA7CA9 | |
| SCHEMBL5713320 | 0.71 | CYP3A4 (0.42) | IDO1CA1CA2CA7CA9 | |
| SCHEMBL7933208 | 0.71 | CA1 (0.40) | IDO1CA1CA2CA7CA9 | |
| SCHEMBL13499 | 0.71 | — | — | |
| SCHEMBL2886150 | 0.69 | IDO1 (0.39) | IDO1CA1CA2CA7CA9 | |
| SCHEMBL2153517 | 0.69 | CA1 (0.38) | IDO1CA1CA2CA7CA9 | |
| SCHEMBL2539209 | 0.69 | ACHE (0.45) | IDO1CA1CA2CA7CA9 | |
| Hydrochloric Acid SCHEMBL21724713 | 0.69 | CYP3A4 (0.40) | IDO1CA1CA2CA7CA9 | |
| SCHEMBL10340770 | 0.69 | LMNA (0.50) | IDO1CA1CA2CA7CA9 | |
| SCHEMBL19968353 | 0.69 | IDO1 (0.39) | IDO1CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0170102-B1 | PROCESS FOR PREPARING BIFUNCTIONAL TERTIARY AROMATIC PHOSPHINE SULPHIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-03-14 | — | — | EP | disclosed |
| EP-0230243-B1 | PROCESS FOR THE PREPARATION OF BIFUNCTIONAL TERTIARY AROMATIC PHOSPHANSULFIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-03-07 | — | — | EP | disclosed |